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Tal1/SCL binding to pericentromeric DNA represses transcription
Jie Wen
,
Suming Huang
, Svetlana D. Pack
, Xiaobing Yu
, Stephen J. Brandt
, Constance Tom Noguchi
Department of Pediatrics
Division of Hematology and Oncology
Penn State Cancer Institute
Cancer Institute, Mechanisms of Carcinogenesis
Department of Molecular and Precision Medicine
Research output
:
Contribution to journal
›
Article
›
peer-review
16
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Scopus citations
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Dive into the research topics of 'Tal1/SCL binding to pericentromeric DNA represses transcription'. Together they form a unique fingerprint.
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Biochemistry, Genetics and Molecular Biology
Transcription
100%
Heterochromatin
100%
Chromatin
100%
Promoter Region
33%
Reporter Gene
33%
DNA Binding
33%
Molecular Cloning
33%
Methylation
33%
Histone Deacetylase
33%
Histone H3
33%
Chromatin Immunoprecipitation
33%
Gene Inactivation
33%
Methyltransferase
33%
Heterochromatin Protein 1
33%
E-Box
33%
Hematopoiesis
33%
Basic Helix Loop Helix Transcription Factor
33%
Trichostatin A
33%
Lysine
33%
Genomics
33%
Expression Level
33%
Keyphrases
TAL1
100%
Chromatin
23%
Binding Motif
15%
Heterochromatin
15%
SUV39H1
15%
H3K9me3
15%
Lysine
7%
Genomic DNA (gDNA)
7%
Transcriptional Regulation
7%
Expression Level
7%
Histone Deacetylase Inhibitor (HDACi)
7%
Cis-acting
7%
Chromatin Immunoprecipitation (ChIP)
7%
Histone H3
7%
Interaction Partner
7%
Transcriptional Repression
7%
Basic Helix-loop-helix (bHLH)
7%
Gene Inactivation
7%
Novel Mechanism of Action
7%
Reporter Gene Assay
7%
Methyltransferase
7%
Heterochromatin Proteins
7%
Pericentromeric Region
7%
E-box
7%
K562
7%
In Vitro DNA Binding
7%
H3K9 Methylation
7%
Erythroleukemia Cells
7%
Trichostatin A
7%
Hypermethylation
7%
Normal Hematopoiesis
7%
Factor-critical
7%