Talking about recommended age or fewer doses: what motivates HPV vaccination timeliness?

HPV vaccination is recommended for U.S. adolescents at ages 11–12 and requires two versus three doses if the series is started before age 15. We evaluated how talking about recommended age or fewer doses motivates on-time HPV vaccination. Our national, online experiment randomized 1,263 parents of adolescents to view one of three messages about HPV vaccination recommendations or no message. Messages framed guidelines as recommending: vaccination at age 11–12; fewer doses for those who start vaccination at age 11–12; or, fewer doses for those who start vaccination before age 15. We then assessed parents’ preferred age for HPV vaccination, categorizing preferences of ≤12 years as on-time. Parents who viewed “at age 11–12” versus no message more often preferred on-time HPV vaccination (63% vs. 43%, p < .05) and did not differ from those viewing “fewer doses at age 11–12” (63% vs. 64%, p > .05). Parents who viewed “fewer doses before age 15” less often preferred on-time HPV vaccination (39%, p < .05). Recommending HPV vaccination at age 11–12 encouraged on-time vaccination, while offering fewer doses had little impact. Providers should avoid framing HPV vaccination guidelines in reference to age 15 because doing so may discourage on-time vaccination by introducing confusion about the recommended age.