Targeting structural dynamics of the RNA-dependent RNA polymerase for anti-viral strategies

Keyphrases

• Polymerase 100%
• Antiviral Strategy 100%
• RNA-dependent RNA Polymerase (RdRP) 100%
• Structural Dynamics 100%
• Virus 40%
• Molecular Dynamics Simulation 20%
• Amino Acid Substitution 20%
• Nuclear Magnetic Resonance Experiment 20%
• Small Molecule Binding 20%
• Active Loop 20%
• RNA Virus 20%
• Protein Motion 20%
• Genome Replication 20%
• Attenuated Vaccine Strains 20%
• Internal Proteins 20%
• Live Attenuated Vaccine 20%

Pharmacology, Toxicology and Pharmaceutical Science

• RNA Directed RNA Polymerase 100%
• Antivirus Agent 100%
• Drug Development 50%
• Amino Acid 50%
• Virus RNA 50%
• Vaccine Strain 50%
• Live Vaccine 50%

Biochemistry, Genetics and Molecular Biology

• Polymerase 100%
• Dynamics 100%
• RNA-dependent RNA Polymerase 100%
• Motion 40%
• Small Molecule 20%
• Magnetism 20%
• Active Site 20%
• Amino Acid Substitution 20%
• RNA Virus 20%