Taxonomy of pathogen codetection in pediatric case fatalities with adenoviral respiratory infection

Emily K. Ninmer, Claire Stewart, Matthew P. Sharron, Julia Noether Ashworth, Natalia Martinez-Schlurman, Robert P. Kavanagh, Jessica K. Signoff, Michael C. McCrory, Daniel B. Eidman, Anjali V. Subbaswamy, Paul L. Shea, Mary Lynn Sheram, Christopher M. Watson, Michael C. Spaeder

Research output: Contribution to journalArticlepeer-review

Abstract

Objective The aim of this study was to determine the prevalence and taxonomy of pathogen codetection in pediatric case fatalities associated with adenoviral respiratory infection. Methods This retrospective case series included 107 pediatric case fatalities associated with adenoviral respiratory infection. Results We observed a high rate of pathogen codetection with broad diversity from both respiratory and nonrespiratory sources. We noted differences in codetection characteristics based on immune status; most notably that immunocompromised cases were more likely to have bacteremia and adenoviremia. Conclusions In pediatric case fatalities associated with adenoviral respiratory infection, we observed a high degree of pathogen codetection.

Original languageEnglish (US)
Pages (from-to)194-199
Number of pages6
JournalJournal of Pediatric Infectious Diseases
Volume16
Issue number5
DOIs
StatePublished - Sep 1 2021

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases

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