TY - JOUR
T1 - Testicular suture
T2 - A significant risk factor for infertility among formerly cryptorchid men
AU - Coughlin, Michael T.
AU - Bellinger, Mark F.
AU - LaPorte, Ronald E.
AU - Lee, Peter A.
N1 - Funding Information:
From the Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Department of Pediatrics, University of Pittsburgh School of Medicine; and Children’s Hospital oj Pittsburgh, Pittsburgh, PA. This paper is made possible in part by Grant 1ROl HD26477from the National Institutes of Health and a grant from the Genentech Foundation for Growth and Development. Address reprint requests to Peter A. Lee, MD, PhD, Children’s Hospital of Pittsburgh, Division of Endocrinology, 3705 Fifth Ave, Pittsburgh, PA 15213. Copyright 0 1998 by KB. Saunders Company 0022.3468/98/3312-0013$03.00/O bilateral cryptorchidism (RR, 5.51; 95% Cl, 1.58,19.24), cele (RR, 4.72; 95% Cl, 1.42,15.75), hormone treatment surgery (RR, 3.69; 95% Cl, 1.22, 11 .I I), and partner tion problem (RR, 3.32; 95% Cl, 1.11,9.90).
PY - 1998/12
Y1 - 1998/12
N2 - Background/Purpose: Although fertility is decreased after cryptorchidism, the importance of risk factors, including parenchymal testicular suture, is unknown. The aim of this study was to examine the relationship between parenchymal testicular suture and failure to conceive a child for 1 year or longer among formerly cryptorchid men. Methods: Men who underwent orchidopexy between 1955 and 1972 at the Children's Hospital of Pittsburgh (n = 619) were surveyed by questionnaire and their medical records reviewed. Only the men who attempted to conceive a child (n = 387) are included. Results: Logistic regression analysis determined significant risk factors far infertility. Testicular suture was strongly related to infertility (RR, 7.56; 95% CI, 1.66, 34.39) as were bilateral cryptorchidism (RR, 5.51; 95% CI, 1.58, 19.24), varicocele (RR, 4.72; 95% CI, 1.42, 15.75), hormone treatment before surgery (RR, 3.69; 95% CI, 1.22, 11.11), and partner conception problem (RR, 3.32; 95% CI, 1.11, 9.90). Conclusions: Testicular suture was a potent independent determinant of infertility among formerly cryptorchid men who have orchidopexy. Bilateral cryptorchidism, hormone treatment, varicocele, and partner conception problems also were associated with increased infertility.
AB - Background/Purpose: Although fertility is decreased after cryptorchidism, the importance of risk factors, including parenchymal testicular suture, is unknown. The aim of this study was to examine the relationship between parenchymal testicular suture and failure to conceive a child for 1 year or longer among formerly cryptorchid men. Methods: Men who underwent orchidopexy between 1955 and 1972 at the Children's Hospital of Pittsburgh (n = 619) were surveyed by questionnaire and their medical records reviewed. Only the men who attempted to conceive a child (n = 387) are included. Results: Logistic regression analysis determined significant risk factors far infertility. Testicular suture was strongly related to infertility (RR, 7.56; 95% CI, 1.66, 34.39) as were bilateral cryptorchidism (RR, 5.51; 95% CI, 1.58, 19.24), varicocele (RR, 4.72; 95% CI, 1.42, 15.75), hormone treatment before surgery (RR, 3.69; 95% CI, 1.22, 11.11), and partner conception problem (RR, 3.32; 95% CI, 1.11, 9.90). Conclusions: Testicular suture was a potent independent determinant of infertility among formerly cryptorchid men who have orchidopexy. Bilateral cryptorchidism, hormone treatment, varicocele, and partner conception problems also were associated with increased infertility.
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U2 - 10.1016/S0022-3468(98)90286-X
DO - 10.1016/S0022-3468(98)90286-X
M3 - Article
C2 - 9869052
AN - SCOPUS:0031649508
SN - 0022-3468
VL - 33
SP - 1790
EP - 1793
JO - Journal of pediatric surgery
JF - Journal of pediatric surgery
IS - 12
ER -