Tetrahedron DNA dendrimers and their encapsulation of gold nanoparticles

Tao Zhou; Yijie Wang; Yuanchen Dong; Chun Chen; Dongsheng Liu; Zhongqiang Yang

doi:10.1016/j.bmc.2014.05.062

Tetrahedron DNA dendrimers and their encapsulation of gold nanoparticles

Tao Zhou
, Yijie Wang
, Yuanchen Dong
, Chun Chen
, Dongsheng Liu
, Zhongqiang Yang

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

DNA dendrimers have achieved increasing attention recently. Previously reported DNA dendrimers used Y-DNA as monomers. Tetrahedron DNA is a rigid tetrahedral cage made of DNA. Herein, we use tetrahedron DNA as monomers to prepare tetrahedron DNA dendrimers. The prepared tetrahedron DNA dendrimers have larger size compared with those made of Y-DNA. In addition, thanks to the central cavity of tetrahedron DNA monomers, some nanoscale structures (e.g., gold nanoparticles) can be encapsulated within tetrahedron DNA monomers. Tetrahedron DNA encapsulated with gold nanoparticles can be further assembled into dendrimers, guiding gold nanoparticles into clusters.

Original language	English (US)
Pages (from-to)	4391-4394
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry
Volume	22
Issue number	16
DOIs	https://doi.org/10.1016/j.bmc.2014.05.062
State	Published - Aug 15 2014

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

Access to Document

10.1016/j.bmc.2014.05.062

Cite this

@article{90c87f667f5a44b8bd26128dca78edb0,

title = "Tetrahedron DNA dendrimers and their encapsulation of gold nanoparticles",

abstract = "DNA dendrimers have achieved increasing attention recently. Previously reported DNA dendrimers used Y-DNA as monomers. Tetrahedron DNA is a rigid tetrahedral cage made of DNA. Herein, we use tetrahedron DNA as monomers to prepare tetrahedron DNA dendrimers. The prepared tetrahedron DNA dendrimers have larger size compared with those made of Y-DNA. In addition, thanks to the central cavity of tetrahedron DNA monomers, some nanoscale structures (e.g., gold nanoparticles) can be encapsulated within tetrahedron DNA monomers. Tetrahedron DNA encapsulated with gold nanoparticles can be further assembled into dendrimers, guiding gold nanoparticles into clusters.",

author = "Tao Zhou and Yijie Wang and Yuanchen Dong and Chun Chen and Dongsheng Liu and Zhongqiang Yang",

note = "Funding Information: We thank the National Natural Science Foundation of China ( 21174077 , 91027046 , 21121004 ), the National Basic Research Program of China ( 2013CB932803 ) and Beijing Municipal Science \& Technology Commission for financial support. ",

year = "2014",

month = aug,

day = "15",

doi = "10.1016/j.bmc.2014.05.062",

language = "English (US)",

volume = "22",

pages = "4391--4394",

journal = "Bioorganic and Medicinal Chemistry",

issn = "0968-0896",

publisher = "Elsevier Ltd",

number = "16",

}

TY - JOUR

T1 - Tetrahedron DNA dendrimers and their encapsulation of gold nanoparticles

AU - Zhou, Tao

AU - Wang, Yijie

AU - Dong, Yuanchen

AU - Chen, Chun

AU - Liu, Dongsheng

AU - Yang, Zhongqiang

N1 - Funding Information: We thank the National Natural Science Foundation of China ( 21174077 , 91027046 , 21121004 ), the National Basic Research Program of China ( 2013CB932803 ) and Beijing Municipal Science & Technology Commission for financial support.

PY - 2014/8/15

Y1 - 2014/8/15

N2 - DNA dendrimers have achieved increasing attention recently. Previously reported DNA dendrimers used Y-DNA as monomers. Tetrahedron DNA is a rigid tetrahedral cage made of DNA. Herein, we use tetrahedron DNA as monomers to prepare tetrahedron DNA dendrimers. The prepared tetrahedron DNA dendrimers have larger size compared with those made of Y-DNA. In addition, thanks to the central cavity of tetrahedron DNA monomers, some nanoscale structures (e.g., gold nanoparticles) can be encapsulated within tetrahedron DNA monomers. Tetrahedron DNA encapsulated with gold nanoparticles can be further assembled into dendrimers, guiding gold nanoparticles into clusters.

AB - DNA dendrimers have achieved increasing attention recently. Previously reported DNA dendrimers used Y-DNA as monomers. Tetrahedron DNA is a rigid tetrahedral cage made of DNA. Herein, we use tetrahedron DNA as monomers to prepare tetrahedron DNA dendrimers. The prepared tetrahedron DNA dendrimers have larger size compared with those made of Y-DNA. In addition, thanks to the central cavity of tetrahedron DNA monomers, some nanoscale structures (e.g., gold nanoparticles) can be encapsulated within tetrahedron DNA monomers. Tetrahedron DNA encapsulated with gold nanoparticles can be further assembled into dendrimers, guiding gold nanoparticles into clusters.

UR - https://www.scopus.com/pages/publications/84906265109

UR - https://www.scopus.com/pages/publications/84906265109#tab=citedBy

U2 - 10.1016/j.bmc.2014.05.062

DO - 10.1016/j.bmc.2014.05.062

M3 - Article

C2 - 24953949

AN - SCOPUS:84906265109

SN - 0968-0896

VL - 22

SP - 4391

EP - 4394

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

IS - 16

ER -

Tetrahedron DNA dendrimers and their encapsulation of gold nanoparticles

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this