Tetrahydrofuran synthesis via free radical mediated addition of functionalized alkenes to aryl vinyl oxiranes

Ken S. Feldman; Thorsten E. Fisher

doi:10.1016/S0040-4020(01)80124-1

Tetrahydrofuran synthesis via free radical mediated addition of functionalized alkenes to aryl vinyl oxiranes

Ken S. Feldman, Thorsten E. Fisher

Chemistry

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

Tri- and tetrasubstituted tetrahydrofuran rings can be prepared by phenylthio radical mediated addition of functionalized alkenes across the carbon-carbon bond of aryl substituted vinyl oxiranes. Studies designed both to delineate the scope and limitations and elucidate the mechanistic course of this process are described.

Original language	English (US)
Pages (from-to)	2969-2977
Number of pages	9
Journal	Tetrahedron
Volume	45
Issue number	10
DOIs	https://doi.org/10.1016/S0040-4020(01)80124-1
State	Published - 1989

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4020(01)80124-1

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title = "Tetrahydrofuran synthesis via free radical mediated addition of functionalized alkenes to aryl vinyl oxiranes",

abstract = "Tri- and tetrasubstituted tetrahydrofuran rings can be prepared by phenylthio radical mediated addition of functionalized alkenes across the carbon-carbon bond of aryl substituted vinyl oxiranes. Studies designed both to delineate the scope and limitations and elucidate the mechanistic course of this process are described.",

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AU - Feldman, Ken S.

AU - Fisher, Thorsten E.

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N2 - Tri- and tetrasubstituted tetrahydrofuran rings can be prepared by phenylthio radical mediated addition of functionalized alkenes across the carbon-carbon bond of aryl substituted vinyl oxiranes. Studies designed both to delineate the scope and limitations and elucidate the mechanistic course of this process are described.

AB - Tri- and tetrasubstituted tetrahydrofuran rings can be prepared by phenylthio radical mediated addition of functionalized alkenes across the carbon-carbon bond of aryl substituted vinyl oxiranes. Studies designed both to delineate the scope and limitations and elucidate the mechanistic course of this process are described.

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U2 - 10.1016/S0040-4020(01)80124-1

DO - 10.1016/S0040-4020(01)80124-1

M3 - Article

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JO - Tetrahedron

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Tetrahydrofuran synthesis via free radical mediated addition of functionalized alkenes to aryl vinyl oxiranes

Abstract

All Science Journal Classification (ASJC) codes

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