TY - JOUR
T1 - The Association Between Maternal Prenatal Fish Intake and Child Autism-Related Traits in the EARLI and HOME Studies
AU - Vecchione, Rachel
AU - Vigna, Chelsea
AU - Whitman, Casey
AU - Kauffman, Elizabeth M.
AU - Braun, Joseph M.
AU - Chen, Aimin
AU - Xu, Yingying
AU - Hamra, Ghassan B.
AU - Lanphear, Bruce P.
AU - Yolton, Kimberly
AU - Croen, Lisa A.
AU - Fallin, M. Daniele
AU - Irva Hertz-Picciotto, Hertz-Picciotto
AU - Newschaffer, Craig J.
AU - Lyall, Kristen
N1 - Publisher Copyright:
© 2020, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2021/2
Y1 - 2021/2
N2 - We examined the association between prenatal fish intake and child autism-related traits according to Social Responsiveness Scale (SRS) and cognitive development scores in two US prospective pregnancy cohorts. In adjusted linear regression analyses, higher maternal fish intake in the second half of pregnancy was associated with increased child autism traits (higher raw SRS scores; ß = 5.60, 95%CI 1.76, 12.97). Differences by fish type were suggested; shellfish and large fish species were associated with increases, and salmon with decreases, in child SRS scores. Clear patterns with cognitive scores in the two cohorts were not observed. Future work should further evaluate potential critical windows of prenatal fish intake, and the role of different fish types in association with child autism-related outcomes.
AB - We examined the association between prenatal fish intake and child autism-related traits according to Social Responsiveness Scale (SRS) and cognitive development scores in two US prospective pregnancy cohorts. In adjusted linear regression analyses, higher maternal fish intake in the second half of pregnancy was associated with increased child autism traits (higher raw SRS scores; ß = 5.60, 95%CI 1.76, 12.97). Differences by fish type were suggested; shellfish and large fish species were associated with increases, and salmon with decreases, in child SRS scores. Clear patterns with cognitive scores in the two cohorts were not observed. Future work should further evaluate potential critical windows of prenatal fish intake, and the role of different fish types in association with child autism-related outcomes.
UR - https://www.scopus.com/pages/publications/85086157231
UR - https://www.scopus.com/pages/publications/85086157231#tab=citedBy
U2 - 10.1007/s10803-020-04546-9
DO - 10.1007/s10803-020-04546-9
M3 - Article
C2 - 32519188
AN - SCOPUS:85086157231
SN - 0162-3257
VL - 51
SP - 487
EP - 500
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 2
ER -