TY - JOUR
T1 - The association between poor diet quality, physical fatigability and physical function in the oldest-old from the geisinger rural aging study
AU - Davis, Brett
AU - Liu, Yi Hsuan
AU - Stampley, James
AU - Craig Wood, G.
AU - Mitchell, Diane C.
AU - Jensen, Gordon L.
AU - Gao, Xiang
AU - Glynn, Nancy W.
AU - Still, Christopher D.
AU - Irving, Brian A.
N1 - Funding Information:
Conflicts of Interest: Davis, Liu, Stampley, Glynn, and Gao have nothing to disclose. Jensen, Mitchell, Still, Wood, and Irving report grants United States Department of Agriculture during the study. Still also has grants from Ethicon Endosurgery, other from Novo Nordisk, outside the submitted work. Irving has a grant from the Watermelon Board (subcontract) outside the submitted work. Glynn was supported by the National Institute of Health to develop the Pittsburgh Fatigability Scale.
Funding Information:
Funding: This study is funded by the United States Department of Agriculture, Agricultural Research Service agreement 8050-51530-012-01A. The present analyses were also partially supported by NIH 5R21AG058181 and LSU Biomedical Collaborative Research Program (B.A.I.). J.S. was supported by an Economic Development Assistantship from Louisiana State University. Additionally, the Claude D. Pepper Older Americans Independence Center, Research Registry and Developmental Pilot Grant NIH P30 AG024827, and the Intramural Research Program at the National Institute on Aging supported NWG to develop the Pittsburgh Fatigability Scale. This publication was also supported by the Louisiana State University’s Library Open Access Author Fund (B.D.).
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021
Y1 - 2021
N2 - More perceived physical fatigability and poor diet quality are associated with impairments in physical function in older adults. However, the degree to which more perceived fatigability explains the association between poor diet quality and low physical function is unknown. We examined this relationship in 122 (66F, 56M) of the oldest-old participants from the Geisinger Rural Aging Study (GRAS). We used 24-h dietary recalls to assess the Healthy Eating Index (HEI), the Pittsburgh Fatigability Scale (PFS, 0–50) to assess perceived physical fatigability, and the PROMIS Physical Function 20a* to assess physical function. We grouped participants into three age categories: 80–84 (n = 51), 85–89 (n = 51), and 90+ (n = 20) years. Multiple linear regression revealed that a lower HEI was associated with higher PFS Physical score after adjusting for age group, sex, body mass index, and the number of medical conditions (p = 0.001). Several macro-and micro-nutrient intakes were also lower in those reporting more (≥15) compared to less (<15) perceived physical fatigability. Mediation analysis revealed that PFS Physical scores explained ~65% (p = 0.001) of the association between HEI total score and PROMIS19 Physical Function score. Poor diet quality may contribute to more perceived physical fatigability, which could exacerbate impairments in the oldest-old’s physical function.
AB - More perceived physical fatigability and poor diet quality are associated with impairments in physical function in older adults. However, the degree to which more perceived fatigability explains the association between poor diet quality and low physical function is unknown. We examined this relationship in 122 (66F, 56M) of the oldest-old participants from the Geisinger Rural Aging Study (GRAS). We used 24-h dietary recalls to assess the Healthy Eating Index (HEI), the Pittsburgh Fatigability Scale (PFS, 0–50) to assess perceived physical fatigability, and the PROMIS Physical Function 20a* to assess physical function. We grouped participants into three age categories: 80–84 (n = 51), 85–89 (n = 51), and 90+ (n = 20) years. Multiple linear regression revealed that a lower HEI was associated with higher PFS Physical score after adjusting for age group, sex, body mass index, and the number of medical conditions (p = 0.001). Several macro-and micro-nutrient intakes were also lower in those reporting more (≥15) compared to less (<15) perceived physical fatigability. Mediation analysis revealed that PFS Physical scores explained ~65% (p = 0.001) of the association between HEI total score and PROMIS19 Physical Function score. Poor diet quality may contribute to more perceived physical fatigability, which could exacerbate impairments in the oldest-old’s physical function.
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U2 - 10.3390/GERIATRICS6020041
DO - 10.3390/GERIATRICS6020041
M3 - Article
AN - SCOPUS:85105408332
SN - 2308-3417
VL - 6
JO - Geriatrics (Switzerland)
JF - Geriatrics (Switzerland)
IS - 2
M1 - 41
ER -