TY - JOUR
T1 - The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function
T2 - A Preliminary Report
AU - Karbownik, Michał Seweryn
AU - Hicks, Steven Daniel
N1 - Publisher Copyright:
Copyright © 2022 Karbownik and Hicks.
PY - 2022/5/31
Y1 - 2022/5/31
N2 - Background: Serotonin plays an important role in mood regulation and depression. However, it is not clear whether the levels of serotonin in saliva are related to current mood. Aim: To test the association of salivary serotonin concentrations with mood, as well as cardiovascular and autonomic parameters. Materials and Methods: Saliva samples were obtained from collegiate runners and output parameters were examined before and after physical activity. Results: Salivary serotonin concentration was negatively associated with current mood (β = −0.32, 95%CI −0.62 to −0.02, p = 0.037, analysis adjusted for potential confounders), but insignificantly with measured cardiovascular and autonomic parameters. Conclusions: Salivary serotonin may reflect current mood. The results are preliminary and require further evaluation.
AB - Background: Serotonin plays an important role in mood regulation and depression. However, it is not clear whether the levels of serotonin in saliva are related to current mood. Aim: To test the association of salivary serotonin concentrations with mood, as well as cardiovascular and autonomic parameters. Materials and Methods: Saliva samples were obtained from collegiate runners and output parameters were examined before and after physical activity. Results: Salivary serotonin concentration was negatively associated with current mood (β = −0.32, 95%CI −0.62 to −0.02, p = 0.037, analysis adjusted for potential confounders), but insignificantly with measured cardiovascular and autonomic parameters. Conclusions: Salivary serotonin may reflect current mood. The results are preliminary and require further evaluation.
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U2 - 10.3389/fpsyt.2022.788153
DO - 10.3389/fpsyt.2022.788153
M3 - Article
C2 - 35711584
AN - SCOPUS:85132275302
SN - 1664-0640
VL - 13
JO - Frontiers in Psychiatry
JF - Frontiers in Psychiatry
M1 - 788153
ER -