In an age of molecular genetics, viable but not culturable organisms, and highly sophisticated DNA sequence analysis technologies, is there a chance for a new breakthrough? It is quite extraordinary that 99% of microorganisms not only can't be cultured but are totally unknown to the scientific community. Many bacterial gene functions and identifications in the environment have been uncovered by recent advances in metagenomics or culture-independent genomic analysis in addition to the DNA microarray technology. Our knowledge of detecting and classifying bacterial isolates has been also improved by cutting-edge molecular tools such as biosensors and molecular subtyping as well as phage recombinant probes. Microbial communities, many to be discovered, are slowly revealed by these sharp scientific discoveries.
|Title of host publication
|DNA Research, Genetics and Cell Biology
|Nova Science Publishers, Inc.
|Number of pages
|Published - Dec 1 2011
All Science Journal Classification (ASJC) codes
- General Biochemistry, Genetics and Molecular Biology