The effect of cell shape on local hydrodynamic environment

Yi Fu; Ying Fang; Jianhua Wu; Cheng Dong

doi:10.1109/ITiME.2011.6130895

The effect of cell shape on local hydrodynamic environment

Yi Fu, Ying Fang, Jianhua Wu, Cheng Dong

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Cell adhesion is very important for various biological phenomena in blood flow. Cells would deform to resist the hydrodynamic forces on the blood vessel wall, which results in local flow environment change due to the disturbance of adherent cells. In this paper, computational fluid dynamics simulations were performed to investigate the effect of cell shape on local hydrodynamic environment in details. We found that under a flow condition 73 l/min, cell shape would more affect the flow in one cell height region. Moreover, cell length, the position of cell top and cell shape curvature may also affect the local hydrodynamic environment as well as the drag forces differently.

Original language	English (US)
Title of host publication	ITME 2011 - Proceedings
Subtitle of host publication	2011 IEEE International Symposium on IT in Medicine and Education
Pages	540-543
Number of pages	4
DOIs	https://doi.org/10.1109/ITiME.2011.6130895
State	Published - 2011
Event	2011 IEEE International Symposium on IT in Medicine and Education, ITME 2011 - Guangzhou, China Duration: Dec 9 2011 → Dec 11 2011

Publication series

Name	ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education
Volume	1

Other

Other	2011 IEEE International Symposium on IT in Medicine and Education, ITME 2011
Country/Territory	China
City	Guangzhou
Period	12/9/11 → 12/11/11

All Science Journal Classification (ASJC) codes

Computer Science Applications
Biomedical Engineering
Education

Access to Document

10.1109/ITiME.2011.6130895

Cite this

Fu, Y., Fang, Y., Wu, J., & Dong, C. (2011). The effect of cell shape on local hydrodynamic environment. In ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education (pp. 540-543). Article 6130895 (ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education; Vol. 1). https://doi.org/10.1109/ITiME.2011.6130895

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title = "The effect of cell shape on local hydrodynamic environment",

abstract = "Cell adhesion is very important for various biological phenomena in blood flow. Cells would deform to resist the hydrodynamic forces on the blood vessel wall, which results in local flow environment change due to the disturbance of adherent cells. In this paper, computational fluid dynamics simulations were performed to investigate the effect of cell shape on local hydrodynamic environment in details. We found that under a flow condition 73 l/min, cell shape would more affect the flow in one cell height region. Moreover, cell length, the position of cell top and cell shape curvature may also affect the local hydrodynamic environment as well as the drag forces differently.",

author = "Yi Fu and Ying Fang and Jianhua Wu and Cheng Dong",

year = "2011",

doi = "10.1109/ITiME.2011.6130895",

language = "English (US)",

isbn = "9781612847023",

series = "ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education",

pages = "540--543",

booktitle = "ITME 2011 - Proceedings",

note = "2011 IEEE International Symposium on IT in Medicine and Education, ITME 2011 ; Conference date: 09-12-2011 Through 11-12-2011",

}

Fu, Y, Fang, Y, Wu, J & Dong, C 2011, The effect of cell shape on local hydrodynamic environment. in ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education., 6130895, ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education, vol. 1, pp. 540-543, 2011 IEEE International Symposium on IT in Medicine and Education, ITME 2011, Guangzhou, China, 12/9/11. https://doi.org/10.1109/ITiME.2011.6130895

The effect of cell shape on local hydrodynamic environment. / Fu, Yi; Fang, Ying; Wu, Jianhua et al.
ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education. 2011. p. 540-543 6130895 (ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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N2 - Cell adhesion is very important for various biological phenomena in blood flow. Cells would deform to resist the hydrodynamic forces on the blood vessel wall, which results in local flow environment change due to the disturbance of adherent cells. In this paper, computational fluid dynamics simulations were performed to investigate the effect of cell shape on local hydrodynamic environment in details. We found that under a flow condition 73 l/min, cell shape would more affect the flow in one cell height region. Moreover, cell length, the position of cell top and cell shape curvature may also affect the local hydrodynamic environment as well as the drag forces differently.

AB - Cell adhesion is very important for various biological phenomena in blood flow. Cells would deform to resist the hydrodynamic forces on the blood vessel wall, which results in local flow environment change due to the disturbance of adherent cells. In this paper, computational fluid dynamics simulations were performed to investigate the effect of cell shape on local hydrodynamic environment in details. We found that under a flow condition 73 l/min, cell shape would more affect the flow in one cell height region. Moreover, cell length, the position of cell top and cell shape curvature may also affect the local hydrodynamic environment as well as the drag forces differently.

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ER -

The effect of cell shape on local hydrodynamic environment

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All Science Journal Classification (ASJC) codes

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