The effect of hydrocortisone on lamb lung function

J. W.C. Johnson; H. S. Limb; K. Kearney; H. Abbey; G. H. Brumley; C. J. Migeon; Peter Lee; R. Scott

The effect of hydrocortisone on lamb lung function

J. W.C. Johnson, H. S. Limb, K. Kearney, H. Abbey, G. H. Brumley, C. J. Migeon, Peter Lee, R. Scott

Research output: Contribution to journal › Article › peer-review

Abstract

In this study, administration of hydrocortisone to fetal lambs was associated with an increase in lung volume, but alterations in fetal lung surfactant (as measured by alveolar stability, lung extract surface tensions and phosphatidylcholine concentrations) were not discerned. Our findings support recent rhesus monkey studies suggesting that the principal effect of glucocorticoids is upon nonsurfactant components of the lung.

Original language	English (US)
Pages (from-to)	413-420
Number of pages	8
Journal	Journal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume	26
Issue number	8
State	Published - Oct 26 1981

All Science Journal Classification (ASJC) codes

Reproductive Medicine
Obstetrics and Gynecology

Cite this

@article{86d51c6fa3c84444a45aa64a439efad6,

title = "The effect of hydrocortisone on lamb lung function",

abstract = "In this study, administration of hydrocortisone to fetal lambs was associated with an increase in lung volume, but alterations in fetal lung surfactant (as measured by alveolar stability, lung extract surface tensions and phosphatidylcholine concentrations) were not discerned. Our findings support recent rhesus monkey studies suggesting that the principal effect of glucocorticoids is upon nonsurfactant components of the lung.",

author = "Johnson, {J. W.C.} and Limb, {H. S.} and K. Kearney and H. Abbey and Brumley, {G. H.} and Migeon, {C. J.} and Peter Lee and R. Scott",

year = "1981",

month = oct,

day = "26",

language = "English (US)",

volume = "26",

pages = "413--420",

journal = "Journal of Reproductive Medicine for the Obstetrician and Gynecologist",

issn = "0024-7758",

publisher = "Journal of Reproductive Medicine, Inc.",

number = "8",

}

TY - JOUR

T1 - The effect of hydrocortisone on lamb lung function

AU - Johnson, J. W.C.

AU - Limb, H. S.

AU - Kearney, K.

AU - Abbey, H.

AU - Brumley, G. H.

AU - Migeon, C. J.

AU - Lee, Peter

AU - Scott, R.

PY - 1981/10/26

Y1 - 1981/10/26

N2 - In this study, administration of hydrocortisone to fetal lambs was associated with an increase in lung volume, but alterations in fetal lung surfactant (as measured by alveolar stability, lung extract surface tensions and phosphatidylcholine concentrations) were not discerned. Our findings support recent rhesus monkey studies suggesting that the principal effect of glucocorticoids is upon nonsurfactant components of the lung.

AB - In this study, administration of hydrocortisone to fetal lambs was associated with an increase in lung volume, but alterations in fetal lung surfactant (as measured by alveolar stability, lung extract surface tensions and phosphatidylcholine concentrations) were not discerned. Our findings support recent rhesus monkey studies suggesting that the principal effect of glucocorticoids is upon nonsurfactant components of the lung.

UR - http://www.scopus.com/inward/record.url?scp=0019419096&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019419096&partnerID=8YFLogxK

M3 - Article

C2 - 6895092

AN - SCOPUS:0019419096

SN - 0024-7758

VL - 26

SP - 413

EP - 420

JO - Journal of Reproductive Medicine for the Obstetrician and Gynecologist

JF - Journal of Reproductive Medicine for the Obstetrician and Gynecologist

IS - 8

ER -

The effect of hydrocortisone on lamb lung function

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Fingerprint

Cite this