Abstract
The use of evolution dynamics of model proteins for understanding the similarities between known proteins was discussed. The protein chains were described at a molecular, but simplified level. It was suggested that a number of evolutionary-related quantities, such as the distribution of sequence similarity for structurally similar proteins, are controlled by evolutionary kinetics and do not reflect an equilibrium state. The results for phylogeny show that a subset of the residues of each proteins evolve on a much larger time scale than other residues.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2381-2389 |
| Number of pages | 9 |
| Journal | Journal of Chemical Physics |
| Volume | 121 |
| Issue number | 5 |
| DOIs | |
| State | Published - Aug 1 2004 |
All Science Journal Classification (ASJC) codes
- General Physics and Astronomy
- Physical and Theoretical Chemistry