The evolution of virulence

Andrew F. Read

doi:10.1016/0966-842X(94)90537-1

The evolution of virulence

Andrew F. Read

Research output: Contribution to journal › Review article › peer-review

305 Scopus citations

Abstract

Why is there variation in the virulence of infectious diseases? Virulence can have substantial effects on the genetic contribution of both host and pathogen to future generations. Understanding it therefore requires explanation not only in terms of cellular and molecular mechanisms^{1, 2}, but also in evolutionary terms: what is the nature of the selection acting on genes responsible for virulence?

Original language	English (US)
Pages (from-to)	73-76
Number of pages	4
Journal	Trends in Microbiology
Volume	2
Issue number	3
DOIs	https://doi.org/10.1016/0966-842X(94)90537-1
State	Published - Mar 1994

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases
Virology
Microbiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0966-842X(94)90537-1

Cite this

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title = "The evolution of virulence",

abstract = "Why is there variation in the virulence of infectious diseases? Virulence can have substantial effects on the genetic contribution of both host and pathogen to future generations. Understanding it therefore requires explanation not only in terms of cellular and molecular mechanisms1, 2, but also in evolutionary terms: what is the nature of the selection acting on genes responsible for virulence?",

author = "Read, {Andrew F.}",

note = "Funding Information: I thank J. Bull, B. Levin and S. Nee for helpful comments, My empirical work is funded by The Leverhulme Trust and the AFRC; I am supported by an AFRC Research Fellowship.",

year = "1994",

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doi = "10.1016/0966-842X(94)90537-1",

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AU - Read, Andrew F.

N1 - Funding Information: I thank J. Bull, B. Levin and S. Nee for helpful comments, My empirical work is funded by The Leverhulme Trust and the AFRC; I am supported by an AFRC Research Fellowship.

PY - 1994/3

Y1 - 1994/3

N2 - Why is there variation in the virulence of infectious diseases? Virulence can have substantial effects on the genetic contribution of both host and pathogen to future generations. Understanding it therefore requires explanation not only in terms of cellular and molecular mechanisms1, 2, but also in evolutionary terms: what is the nature of the selection acting on genes responsible for virulence?

AB - Why is there variation in the virulence of infectious diseases? Virulence can have substantial effects on the genetic contribution of both host and pathogen to future generations. Understanding it therefore requires explanation not only in terms of cellular and molecular mechanisms1, 2, but also in evolutionary terms: what is the nature of the selection acting on genes responsible for virulence?

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DO - 10.1016/0966-842X(94)90537-1

M3 - Review article

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SN - 0966-842X

VL - 2

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JO - Trends in Microbiology

JF - Trends in Microbiology

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ER -

The evolution of virulence

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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