The first example of tautomerism in 2-aminopyrroles: effect of structure and solvent

Michael De Rosa; David Arnold; Bernie O'Hare

doi:10.1016/j.tetlet.2008.10.100

The first example of tautomerism in 2-aminopyrroles: effect of structure and solvent

Michael De Rosa, David Arnold, Bernie O'Hare

Penn State Brandywine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Amino/imino tautomerism is observed in secondary 2-aminopyrroles when an electron-withdrawing group is on the amino group. The amino tautomer was favored in solvents that were hydrogen bond acceptors.

Original language	English (US)
Pages (from-to)	12-14
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	1
DOIs	https://doi.org/10.1016/j.tetlet.2008.10.100
State	Published - Jan 7 2009

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2008.10.100

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title = "The first example of tautomerism in 2-aminopyrroles: effect of structure and solvent",

abstract = "Amino/imino tautomerism is observed in secondary 2-aminopyrroles when an electron-withdrawing group is on the amino group. The amino tautomer was favored in solvents that were hydrogen bond acceptors.",

author = "{De Rosa}, Michael and David Arnold and Bernie O'Hare",

note = "Funding Information: This work was supported by grant CHE-0110801 from the National Science Foundation. We thank Dr. Alan Benesi (The Pennsylvania State University) for NMR spectra.",

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AU - Arnold, David

AU - O'Hare, Bernie

N1 - Funding Information: This work was supported by grant CHE-0110801 from the National Science Foundation. We thank Dr. Alan Benesi (The Pennsylvania State University) for NMR spectra.

PY - 2009/1/7

Y1 - 2009/1/7

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AB - Amino/imino tautomerism is observed in secondary 2-aminopyrroles when an electron-withdrawing group is on the amino group. The amino tautomer was favored in solvents that were hydrogen bond acceptors.

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JO - Tetrahedron Letters

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The first example of tautomerism in 2-aminopyrroles: effect of structure and solvent

Abstract

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