TY - JOUR
T1 - The Future of Adult Cardiac Assist Devices
T2 - Novel Systems and Mechanical Circulatory Support Strategies
AU - Bartoli, Carlo R.
AU - Dowling, Robert
PY - 2011/11
Y1 - 2011/11
N2 - The recent, widespread success of mechanical circulatory support has prompted the development of numerous implantable devices to treat advanced heart failure. It is important to raise awareness of novel device systems, the mechanisms by which they function, and implications for patient management. This article discusses devices that are being developed or are in clinical trials. Devices are categorized as standard full support, less-invasive full support, partial support: rotary pumps, partial support: counterpulsation devices, right ventricular assist device, and total artificial heart. Implantation strategy, mechanism of action, durability, efficacy, hemocompatibility, and human factors are considered. The feasibility of novel strategies for unloading the failing heart is examined.
AB - The recent, widespread success of mechanical circulatory support has prompted the development of numerous implantable devices to treat advanced heart failure. It is important to raise awareness of novel device systems, the mechanisms by which they function, and implications for patient management. This article discusses devices that are being developed or are in clinical trials. Devices are categorized as standard full support, less-invasive full support, partial support: rotary pumps, partial support: counterpulsation devices, right ventricular assist device, and total artificial heart. Implantation strategy, mechanism of action, durability, efficacy, hemocompatibility, and human factors are considered. The feasibility of novel strategies for unloading the failing heart is examined.
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U2 - 10.1016/j.ccl.2011.08.013
DO - 10.1016/j.ccl.2011.08.013
M3 - Review article
C2 - 22062206
AN - SCOPUS:80655128356
SN - 0733-8651
VL - 29
SP - 559
EP - 582
JO - Cardiology Clinics
JF - Cardiology Clinics
IS - 4
ER -