The genetic analysis of repeated measures. I. Simplex models

Dorret I. Boomsma, Peter C.M. Molenaar

Research output: Contribution to journalArticlepeer-review

98 Scopus citations


The well-known simplex model is extended to a model that may be used for the genetic and environmental analysis of covariance structures. This "double" simplex structure can be specified as a LISREL model. It is shown that data which give rise to a simplex correlation structure, such as repeated-measures data, do not fit a factor-analysis model. The parameter estimation of the simplex model is illustrated with computer-simulated twin data.

Original languageEnglish (US)
Pages (from-to)111-123
Number of pages13
JournalBehavior Genetics
Issue number2
StatePublished - Mar 1987

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Genetics(clinical)


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