The Goldman Consensus statement on depression in multiple sclerosis

Randolph B. Schiffer, Peter Arnett, Aliza Ben-Zacharia, Ralph Benedict, Julie Bobholz, Lauren Caruso, Gordon Chelune, Darcy Cox, Gary Cutter, Terry DiLorenzo, John DeLuca, Jane Epstein, Anthony Feinstein, Stephen J. Ferrando, Jill Fischer, Fred Foley, Carl Granger, June Halper, Nancy Holland, Jeffery KocsisRosalind Kalb, Nicholas LaRocca, Fred Lublin, Aaron Miller, Deborah Miller, Sarah Minden, David C. Mohr, Linda Morgante, Marie Namey, Scott B. Patten

Research output: Contribution to journalReview articlepeer-review

260 Scopus citations


Background. In January 2002 the New York City Chapter of the National Multiple Sclerosis Society convened a panel of experts to review the issue of depressive affective disorders associated with multiple sclerosis (MS). This Consensus Conference was supported by a grant from the Goldman family of New York City. Results. The panel reviewed summaries of current epidemiologic, neurobiologic, and therapeutic studies having to do with depressive disorders among MS patient populations. Depressive disorders occur at high rates among patients with MS, and there is reason to believe that the immunopathology of the disease is involved in the clinical expression of affective disorders. The depressive syndromes of MS have a major negative impact on quality of life for MS sufferers, but are treatable. At the present time, most MS patients with depression do not receive adequate recognition and treatment. Conclusions. The Goldman Consensus Conference Study Group provides recommendations for improved screening, diagnosis, and clinical management for depressive affective disorders among patients suffering from MS.

Original languageEnglish (US)
Pages (from-to)328-337
Number of pages10
JournalMultiple Sclerosis
Issue number3
StatePublished - Jun 2005

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology


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