The grapes of incompatibility

Jan Klein

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations


When two colonies of the tunicate Botryllus contact each other, they either fuse into a single colony or mount a destructive reaction, which keeps them apart. Which of the two reactions takes place is determined by a single, highly polymorphic fusion/histocompatibility (FuHC) locus. Recent communications report the cloning and characterization of the FuHC locus and suggest that its function may be to protect against parasitism by conspecific stem cells.

Original languageEnglish (US)
Pages (from-to)2-4
Number of pages3
JournalDevelopmental Cell
Issue number1
StatePublished - Jan 2006

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • General Biochemistry, Genetics and Molecular Biology
  • Developmental Biology
  • Cell Biology


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