The grapes of incompatibility

Jan Klein

doi:10.1016/j.devcel.2005.12.009

The grapes of incompatibility

Jan Klein

Biology

Research output: Contribution to journal › Short survey › peer-review

6 Scopus citations

Abstract

When two colonies of the tunicate Botryllus contact each other, they either fuse into a single colony or mount a destructive reaction, which keeps them apart. Which of the two reactions takes place is determined by a single, highly polymorphic fusion/histocompatibility (FuHC) locus. Recent communications report the cloning and characterization of the FuHC locus and suggest that its function may be to protect against parasitism by conspecific stem cells.

Original language	English (US)
Pages (from-to)	2-4
Number of pages	3
Journal	Developmental Cell
Volume	10
Issue number	1
DOIs	https://doi.org/10.1016/j.devcel.2005.12.009
State	Published - Jan 2006

All Science Journal Classification (ASJC) codes

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
Developmental Biology
Cell Biology

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10.1016/j.devcel.2005.12.009

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abstract = "When two colonies of the tunicate Botryllus contact each other, they either fuse into a single colony or mount a destructive reaction, which keeps them apart. Which of the two reactions takes place is determined by a single, highly polymorphic fusion/histocompatibility (FuHC) locus. Recent communications report the cloning and characterization of the FuHC locus and suggest that its function may be to protect against parasitism by conspecific stem cells.",

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AB - When two colonies of the tunicate Botryllus contact each other, they either fuse into a single colony or mount a destructive reaction, which keeps them apart. Which of the two reactions takes place is determined by a single, highly polymorphic fusion/histocompatibility (FuHC) locus. Recent communications report the cloning and characterization of the FuHC locus and suggest that its function may be to protect against parasitism by conspecific stem cells.

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JO - Developmental Cell

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The grapes of incompatibility

Abstract

All Science Journal Classification (ASJC) codes

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