The high mobility group I-C gene (HMGI-C): Polymorphism and genetic localization

C. S. Ishwad; M. D. Shriver; D. M. Lassige; R. E. Ferrell

doi:10.1007/s004390050320

The high mobility group I-C gene (HMGI-C): Polymorphism and genetic localization

C. S. Ishwad, M. D. Shriver, D. M. Lassige, R. E. Ferrell

Anthropology

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Abstract

We have identified a highly informative dinucleotide repeat in the 5'-flanking region of the human high mobility group I-C (HMGI-C) gene. This polymorphism consists of 18-37 copies of a (CT) repeat with an observed heterozygosity of 82-83% in African Americans and Caucasians. Linkage analysis in CEPH pedigrees localized the HMGI-C gene to chromosome region 12q13-15 with no recombination observed between HMCI-C and markers D12S102 and D12S8.

Original language	English (US)
Pages (from-to)	103-105
Number of pages	3
Journal	Human genetics
Volume	99
Issue number	1
DOIs	https://doi.org/10.1007/s004390050320
State	Published - Dec 1996

All Science Journal Classification (ASJC) codes

Genetics
Genetics(clinical)

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abstract = "We have identified a highly informative dinucleotide repeat in the 5'-flanking region of the human high mobility group I-C (HMGI-C) gene. This polymorphism consists of 18-37 copies of a (CT) repeat with an observed heterozygosity of 82-83\% in African Americans and Caucasians. Linkage analysis in CEPH pedigrees localized the HMGI-C gene to chromosome region 12q13-15 with no recombination observed between HMCI-C and markers D12S102 and D12S8.",

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year = "1996",

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volume = "99",

pages = "103--105",

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AU - Lassige, D. M.

AU - Ferrell, R. E.

PY - 1996/12

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AB - We have identified a highly informative dinucleotide repeat in the 5'-flanking region of the human high mobility group I-C (HMGI-C) gene. This polymorphism consists of 18-37 copies of a (CT) repeat with an observed heterozygosity of 82-83% in African Americans and Caucasians. Linkage analysis in CEPH pedigrees localized the HMGI-C gene to chromosome region 12q13-15 with no recombination observed between HMCI-C and markers D12S102 and D12S8.

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The high mobility group I-C gene (HMGI-C): Polymorphism and genetic localization

Abstract

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