TY - JOUR
T1 - The human oxidation field
AU - Zannoni, Nora
AU - Lakey, Pascale S.J.
AU - Won, Youngbo
AU - Shiraiwa, Manabu
AU - Rim, Donghyun
AU - Weschler, Charles J.
AU - Wang, Nijing
AU - Ernle, Lisa
AU - Li, Mengze
AU - Bekö, Gabriel
AU - Wargocki, Pawel
AU - Williams, Jonathan
N1 - Publisher Copyright:
© 2022 American Association for the Advancement of Science. All rights reserved.
PY - 2022/9/2
Y1 - 2022/9/2
N2 - Hydroxyl (OH) radicals are highly reactive species that can oxidize most pollutant gases. In this study, high concentrations of OH radicals were found when people were exposed to ozone in a climate-controlled chamber. OH concentrations calculated by two methods using measurements of total OH reactivity, speciated alkenes, and oxidation products were consistent with those obtained from a chemically explicit model. Key to establishing this human-induced oxidation field is 6-methyl-5-hepten-2-one (6-MHO), which forms when ozone reacts with the skin-oil squalene and subsequently generates OH efficiently through gas-phase reaction with ozone. A dynamic model was used to show the spatial extent of the human-generated OH oxidation field and its dependency on ozone influx through ventilation. This finding has implications for the oxidation, lifetime, and perception of chemicals indoors and, ultimately, human health.
AB - Hydroxyl (OH) radicals are highly reactive species that can oxidize most pollutant gases. In this study, high concentrations of OH radicals were found when people were exposed to ozone in a climate-controlled chamber. OH concentrations calculated by two methods using measurements of total OH reactivity, speciated alkenes, and oxidation products were consistent with those obtained from a chemically explicit model. Key to establishing this human-induced oxidation field is 6-methyl-5-hepten-2-one (6-MHO), which forms when ozone reacts with the skin-oil squalene and subsequently generates OH efficiently through gas-phase reaction with ozone. A dynamic model was used to show the spatial extent of the human-generated OH oxidation field and its dependency on ozone influx through ventilation. This finding has implications for the oxidation, lifetime, and perception of chemicals indoors and, ultimately, human health.
UR - http://www.scopus.com/inward/record.url?scp=85129187563&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85129187563&partnerID=8YFLogxK
U2 - 10.1126/science.abn0340
DO - 10.1126/science.abn0340
M3 - Article
C2 - 36048928
AN - SCOPUS:85129187563
SN - 0036-8075
VL - 377
JO - Science
JF - Science
IS - 6610
M1 - eabn0340
ER -