The Insula in Women with Posttraumatic Stress Disorder

Steven E. Bruce; Katherine R. Buchholz; Wilson J. Brown

doi:10.1002/9781119057840.ch39

The Insula in Women with Posttraumatic Stress Disorder

Steven E. Bruce, Katherine R. Buchholz, Wilson J. Brown

School of Humanities & Social Sciences (Behrend)

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The past decade has seen a significant increase in our understanding of the neurobiological mechanisms of PTSD. This chapter examines the possible role the insula plays in the etiology and maintenance of PTSD symptoms, particularly in women with PTSD. Within the context of the neurocircuitry of PTSD, disruption of insula activity is thought to be associated with numerous PTSD symptoms, including deficits in autobiographical memories and interoceptive cues. Moreover, recent findings of altered functional connectivity of insular subregions in women with PTSD point to important neural pathways underlying fear extinction of traumatic memories. These results may assist in advancing our understanding of current treatment approaches for PTSD as well as aid in the development of new targeted psychological or psychiatric interventions.

Original language	English (US)
Title of host publication	The Wiley Encyclopedia of Health Psychology
Subtitle of host publication	Biological Bases of Health Behavior: Volume 1, The Social Bases of Health Behavior: Volume 2, Clinical Health Psychology and Behavioral Medicine: Volume 3, Special Issues in Health Psychology: Volume 4
Publisher	wiley
Pages	V1:341-V1:352
ISBN (Electronic)	9781119057840
ISBN (Print)	9781119057833
DOIs	https://doi.org/10.1002/9781119057840.ch39
State	Published - Jan 1 2020

All Science Journal Classification (ASJC) codes

General Psychology

Access to Document

10.1002/9781119057840.ch39

Cite this

Bruce, S. E., Buchholz, K. R., & Brown, W. J. (2020). The Insula in Women with Posttraumatic Stress Disorder. In The Wiley Encyclopedia of Health Psychology: Biological Bases of Health Behavior: Volume 1, The Social Bases of Health Behavior: Volume 2, Clinical Health Psychology and Behavioral Medicine: Volume 3, Special Issues in Health Psychology: Volume 4 (pp. V1:341-V1:352). wiley. https://doi.org/10.1002/9781119057840.ch39

Bruce, Steven E. ; Buchholz, Katherine R. ; Brown, Wilson J. / The Insula in Women with Posttraumatic Stress Disorder. The Wiley Encyclopedia of Health Psychology: Biological Bases of Health Behavior: Volume 1, The Social Bases of Health Behavior: Volume 2, Clinical Health Psychology and Behavioral Medicine: Volume 3, Special Issues in Health Psychology: Volume 4. wiley, 2020. pp. V1:341-V1:352

@inbook{97111c3a724749d0866fb02a4110591b,

title = "The Insula in Women with Posttraumatic Stress Disorder",

abstract = "The past decade has seen a significant increase in our understanding of the neurobiological mechanisms of PTSD. This chapter examines the possible role the insula plays in the etiology and maintenance of PTSD symptoms, particularly in women with PTSD. Within the context of the neurocircuitry of PTSD, disruption of insula activity is thought to be associated with numerous PTSD symptoms, including deficits in autobiographical memories and interoceptive cues. Moreover, recent findings of altered functional connectivity of insular subregions in women with PTSD point to important neural pathways underlying fear extinction of traumatic memories. These results may assist in advancing our understanding of current treatment approaches for PTSD as well as aid in the development of new targeted psychological or psychiatric interventions.",

author = "Bruce, {Steven E.} and Buchholz, {Katherine R.} and Brown, {Wilson J.}",

note = "Publisher Copyright: {\textcopyright} 2021 John Wiley & Sons Ltd.",

year = "2020",

month = jan,

day = "1",

doi = "10.1002/9781119057840.ch39",

language = "English (US)",

isbn = "9781119057833",

pages = "V1:341--V1:352",

booktitle = "The Wiley Encyclopedia of Health Psychology",

publisher = "wiley",

}

Bruce, SE, Buchholz, KR & Brown, WJ 2020, The Insula in Women with Posttraumatic Stress Disorder. in The Wiley Encyclopedia of Health Psychology: Biological Bases of Health Behavior: Volume 1, The Social Bases of Health Behavior: Volume 2, Clinical Health Psychology and Behavioral Medicine: Volume 3, Special Issues in Health Psychology: Volume 4. wiley, pp. V1:341-V1:352. https://doi.org/10.1002/9781119057840.ch39

The Insula in Women with Posttraumatic Stress Disorder. / Bruce, Steven E.; Buchholz, Katherine R.; Brown, Wilson J.
The Wiley Encyclopedia of Health Psychology: Biological Bases of Health Behavior: Volume 1, The Social Bases of Health Behavior: Volume 2, Clinical Health Psychology and Behavioral Medicine: Volume 3, Special Issues in Health Psychology: Volume 4. wiley, 2020. p. V1:341-V1:352.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

TY - CHAP

T1 - The Insula in Women with Posttraumatic Stress Disorder

AU - Bruce, Steven E.

AU - Buchholz, Katherine R.

AU - Brown, Wilson J.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - The past decade has seen a significant increase in our understanding of the neurobiological mechanisms of PTSD. This chapter examines the possible role the insula plays in the etiology and maintenance of PTSD symptoms, particularly in women with PTSD. Within the context of the neurocircuitry of PTSD, disruption of insula activity is thought to be associated with numerous PTSD symptoms, including deficits in autobiographical memories and interoceptive cues. Moreover, recent findings of altered functional connectivity of insular subregions in women with PTSD point to important neural pathways underlying fear extinction of traumatic memories. These results may assist in advancing our understanding of current treatment approaches for PTSD as well as aid in the development of new targeted psychological or psychiatric interventions.

AB - The past decade has seen a significant increase in our understanding of the neurobiological mechanisms of PTSD. This chapter examines the possible role the insula plays in the etiology and maintenance of PTSD symptoms, particularly in women with PTSD. Within the context of the neurocircuitry of PTSD, disruption of insula activity is thought to be associated with numerous PTSD symptoms, including deficits in autobiographical memories and interoceptive cues. Moreover, recent findings of altered functional connectivity of insular subregions in women with PTSD point to important neural pathways underlying fear extinction of traumatic memories. These results may assist in advancing our understanding of current treatment approaches for PTSD as well as aid in the development of new targeted psychological or psychiatric interventions.

UR - http://www.scopus.com/inward/record.url?scp=85210799500&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85210799500&partnerID=8YFLogxK

U2 - 10.1002/9781119057840.ch39

DO - 10.1002/9781119057840.ch39

M3 - Chapter

AN - SCOPUS:85210799500

SN - 9781119057833

SP - V1:341-V1:352

BT - The Wiley Encyclopedia of Health Psychology

PB - wiley

ER -

Bruce SE, Buchholz KR, Brown WJ. The Insula in Women with Posttraumatic Stress Disorder. In The Wiley Encyclopedia of Health Psychology: Biological Bases of Health Behavior: Volume 1, The Social Bases of Health Behavior: Volume 2, Clinical Health Psychology and Behavioral Medicine: Volume 3, Special Issues in Health Psychology: Volume 4. wiley. 2020. p. V1:341-V1:352 doi: 10.1002/9781119057840.ch39

The Insula in Women with Posttraumatic Stress Disorder

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this