The microbiome modulates arbovirus transmission in mosquitoes

Shivanand Hegde; Jason L. Rasgon; Grant L. Hughes

doi:10.1016/j.coviro.2015.08.011

The microbiome modulates arbovirus transmission in mosquitoes

Shivanand Hegde
, Jason L. Rasgon
, Grant L. Hughes

Research output: Contribution to journal › Review article › peer-review

155 Scopus citations

Abstract

Mosquito-transmitted arthropod-borne viruses (arboviruses) such as dengue virus, chikungunya virus, and West Nile virus constitute a major public health burden and are increasing in severity and frequency worldwide. The microbiota associated with mosquitoes (comprised of viruses, bacteria, fungi and protozoa) can profoundly influence many host phenotypes including vector competence, which can either be enhanced or suppressed. Thus, the tripartite interactions between the mosquito vector, its microbiota and the pathogens they transmit offer novel possibilities to control arthropod-borne diseases.

Original language	English (US)
Pages (from-to)	97-102
Number of pages	6
Journal	Current Opinion in Virology
Volume	15
DOIs	https://doi.org/10.1016/j.coviro.2015.08.011
State	Published - Dec 15 2015

All Science Journal Classification (ASJC) codes

Virology

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10.1016/j.coviro.2015.08.011

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@article{f5e2ecf114d943dc9e6bf10365d7292e,

title = "The microbiome modulates arbovirus transmission in mosquitoes",

abstract = "Mosquito-transmitted arthropod-borne viruses (arboviruses) such as dengue virus, chikungunya virus, and West Nile virus constitute a major public health burden and are increasing in severity and frequency worldwide. The microbiota associated with mosquitoes (comprised of viruses, bacteria, fungi and protozoa) can profoundly influence many host phenotypes including vector competence, which can either be enhanced or suppressed. Thus, the tripartite interactions between the mosquito vector, its microbiota and the pathogens they transmit offer novel possibilities to control arthropod-borne diseases.",

author = "Shivanand Hegde and Rasgon, \{Jason L.\} and Hughes, \{Grant L.\}",

note = "Funding Information: This work has been supported by a University of Texas Rising Star Award and Brown Foundation grant to GLH and by NIH/NIAID grants R21AI111175 , R21AI088311 , R56AI116636 and R01AI067371 to JLR. ",

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doi = "10.1016/j.coviro.2015.08.011",

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T1 - The microbiome modulates arbovirus transmission in mosquitoes

AU - Hegde, Shivanand

AU - Rasgon, Jason L.

AU - Hughes, Grant L.

N1 - Funding Information: This work has been supported by a University of Texas Rising Star Award and Brown Foundation grant to GLH and by NIH/NIAID grants R21AI111175 , R21AI088311 , R56AI116636 and R01AI067371 to JLR.

PY - 2015/12/15

Y1 - 2015/12/15

N2 - Mosquito-transmitted arthropod-borne viruses (arboviruses) such as dengue virus, chikungunya virus, and West Nile virus constitute a major public health burden and are increasing in severity and frequency worldwide. The microbiota associated with mosquitoes (comprised of viruses, bacteria, fungi and protozoa) can profoundly influence many host phenotypes including vector competence, which can either be enhanced or suppressed. Thus, the tripartite interactions between the mosquito vector, its microbiota and the pathogens they transmit offer novel possibilities to control arthropod-borne diseases.

AB - Mosquito-transmitted arthropod-borne viruses (arboviruses) such as dengue virus, chikungunya virus, and West Nile virus constitute a major public health burden and are increasing in severity and frequency worldwide. The microbiota associated with mosquitoes (comprised of viruses, bacteria, fungi and protozoa) can profoundly influence many host phenotypes including vector competence, which can either be enhanced or suppressed. Thus, the tripartite interactions between the mosquito vector, its microbiota and the pathogens they transmit offer novel possibilities to control arthropod-borne diseases.

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UR - https://www.scopus.com/pages/publications/84941553728#tab=citedBy

U2 - 10.1016/j.coviro.2015.08.011

DO - 10.1016/j.coviro.2015.08.011

M3 - Review article

C2 - 26363996

AN - SCOPUS:84941553728

SN - 1879-6257

VL - 15

SP - 97

EP - 102

JO - Current Opinion in Virology

JF - Current Opinion in Virology

ER -

The microbiome modulates arbovirus transmission in mosquitoes

Abstract

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