The neural cell spectrin skeleton: a review.

S. R. Goodman, I. S. Zagon

Research output: Contribution to journalReview articlepeer-review

75 Scopus citations


The discovery of nonerythroid spectrin (Goodman et al., Proc. Natl. Acad. Sci. USA 78: 7570-7574, 1981) has generated interest equivalent to that occurring upon the identification of nonmuscle actin and myosin. Brain spectrin has become the best-studied member of the nonerythroid spectrin family of molecules. In this review, we discuss the structure and functional interactions of brain spectrin, as a prelude to attempting to resolve what are some of the more controversial questions in the field. We finish with a discussion of what may be the most profitable directions for future research.

Original languageEnglish (US)
Pages (from-to)C347-360
JournalThe American journal of physiology
Issue number3 Pt 1
StatePublished - Mar 1986

All Science Journal Classification (ASJC) codes

  • Physiology (medical)


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