The Penn State Pediatric Total Artificial Heart

William Weiss; Raymond Newswanger; J. Brian Clark; Jenelle M. Izer

doi:10.1007/978-3-030-47809-4_36

The Penn State Pediatric Total Artificial Heart

William Weiss, Raymond Newswanger, J. Brian Clark, Jenelle M. Izer

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

There is an unmet need for total circulatory support in infants on the waiting list for heart transplantation. Congenital defects and pulmonary dysfunction often require right heart support in addition to systemic support. Penn State is developing a pediatric total artificial heart (TAH) based on a 12 ml pulsatile VAD currently in preclinical testing. The TAH consists of independent left and right pulsatile pumps designed for orthotopic placement. An automatic control system ensures full-to-empty operation, estimates inlet and outlet pressures, and controls right pump output to safely limit left atrial pressure. A portable pneumatic driver has been developed. The TAH has been tested in a juvenile ovine model.

Original language	English (US)
Title of host publication	Mechanical Support for Heart Failure
Subtitle of host publication	Current Solutions and New Technologies
Publisher	Springer International Publishing
Pages	577-585
Number of pages	9
ISBN (Electronic)	9783030478094
ISBN (Print)	9783030478087
DOIs	https://doi.org/10.1007/978-3-030-47809-4_36
State	Published - Jan 1 2020

All Science Journal Classification (ASJC) codes

General Medicine
General Health Professions

Access to Document

10.1007/978-3-030-47809-4_36

Cite this

@inbook{b24b18e299e24a409595ecc482d62898,

title = "The Penn State Pediatric Total Artificial Heart",

abstract = "There is an unmet need for total circulatory support in infants on the waiting list for heart transplantation. Congenital defects and pulmonary dysfunction often require right heart support in addition to systemic support. Penn State is developing a pediatric total artificial heart (TAH) based on a 12 ml pulsatile VAD currently in preclinical testing. The TAH consists of independent left and right pulsatile pumps designed for orthotopic placement. An automatic control system ensures full-to-empty operation, estimates inlet and outlet pressures, and controls right pump output to safely limit left atrial pressure. A portable pneumatic driver has been developed. The TAH has been tested in a juvenile ovine model.",

author = "William Weiss and Raymond Newswanger and Clark, {J. Brian} and Izer, {Jenelle M.}",

note = "Publisher Copyright: {\textcopyright} Springer Nature Switzerland AG 2020.",

year = "2020",

month = jan,

day = "1",

doi = "10.1007/978-3-030-47809-4_36",

language = "English (US)",

isbn = "9783030478087",

pages = "577--585",

booktitle = "Mechanical Support for Heart Failure",

publisher = "Springer International Publishing",

}

TY - CHAP

T1 - The Penn State Pediatric Total Artificial Heart

AU - Weiss, William

AU - Newswanger, Raymond

AU - Clark, J. Brian

AU - Izer, Jenelle M.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - There is an unmet need for total circulatory support in infants on the waiting list for heart transplantation. Congenital defects and pulmonary dysfunction often require right heart support in addition to systemic support. Penn State is developing a pediatric total artificial heart (TAH) based on a 12 ml pulsatile VAD currently in preclinical testing. The TAH consists of independent left and right pulsatile pumps designed for orthotopic placement. An automatic control system ensures full-to-empty operation, estimates inlet and outlet pressures, and controls right pump output to safely limit left atrial pressure. A portable pneumatic driver has been developed. The TAH has been tested in a juvenile ovine model.

AB - There is an unmet need for total circulatory support in infants on the waiting list for heart transplantation. Congenital defects and pulmonary dysfunction often require right heart support in addition to systemic support. Penn State is developing a pediatric total artificial heart (TAH) based on a 12 ml pulsatile VAD currently in preclinical testing. The TAH consists of independent left and right pulsatile pumps designed for orthotopic placement. An automatic control system ensures full-to-empty operation, estimates inlet and outlet pressures, and controls right pump output to safely limit left atrial pressure. A portable pneumatic driver has been developed. The TAH has been tested in a juvenile ovine model.

UR - http://www.scopus.com/inward/record.url?scp=85121594975&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85121594975&partnerID=8YFLogxK

U2 - 10.1007/978-3-030-47809-4_36

DO - 10.1007/978-3-030-47809-4_36

M3 - Chapter

AN - SCOPUS:85121594975

SN - 9783030478087

SP - 577

EP - 585

BT - Mechanical Support for Heart Failure

PB - Springer International Publishing

ER -

The Penn State Pediatric Total Artificial Heart

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Cite this