The Pharmacology of Intrinsic Factor Secretion in Man

Graham H. Jeffries, Marvin H. Sleisenger

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

An in vitro technique based on the interaction between intrinsic factor and intrinsic factor antibody, was used to measure gastric intrinsic factor secretion following histamine, betazole hydrochloride, and methacholine stimulation in man. The secretion of intrinsic factor was augmented by each of these gastric secretory stimuli. The maximal secretion of intrinsic factor was observed during the first 15 min of stimulation and preceded the maximal secretion of acid and water.

Original languageEnglish (US)
Pages (from-to)444-448
Number of pages5
JournalGastroenterology
Volume48
Issue number4
DOIs
StatePublished - 1965

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

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