TY - JOUR
T1 - The Regulation of Mitochondrial Replacement Techniques around the World
AU - Cohen, I. Glenn
AU - Adashi, Eli Y.
AU - Gerke, Sara
AU - Palacios-Gonzaacutelez, Ceacutesar
AU - Ravitsky, Vardit
N1 - Publisher Copyright:
© 2020 Annual Reviews Inc.. All rights reserved.
PY - 2020/8/31
Y1 - 2020/8/31
N2 - Mitochondrial replacement techniques (MRTs, also referred to as mitochondrial replacement therapies) have given hope to many women who wish to have genetically related children but have mitochondrial DNA mutations in their eggs. MRTs have also spurred deep ethical disagreements and led to different regulatory approaches worldwide. In this review, we discuss the current regulation of MRTs across several countries. After discussing the basics of the science, we describe the current law and policy directions in seven countries: The United Kingdom, the United States, Canada, Australia, Germany, Israel, and Singapore. We also discuss the emerging phenomenon of medical tourism (also called medical travel) for MRTs to places like Greece, Spain, Mexico, and Ukraine. We then pull out some key findings regarding similarities and differences in regulatory approaches around the world.
AB - Mitochondrial replacement techniques (MRTs, also referred to as mitochondrial replacement therapies) have given hope to many women who wish to have genetically related children but have mitochondrial DNA mutations in their eggs. MRTs have also spurred deep ethical disagreements and led to different regulatory approaches worldwide. In this review, we discuss the current regulation of MRTs across several countries. After discussing the basics of the science, we describe the current law and policy directions in seven countries: The United Kingdom, the United States, Canada, Australia, Germany, Israel, and Singapore. We also discuss the emerging phenomenon of medical tourism (also called medical travel) for MRTs to places like Greece, Spain, Mexico, and Ukraine. We then pull out some key findings regarding similarities and differences in regulatory approaches around the world.
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U2 - 10.1146/annurev-genom-111119-101815
DO - 10.1146/annurev-genom-111119-101815
M3 - Review article
C2 - 31961722
AN - SCOPUS:85090249669
SN - 1527-8204
VL - 21
SP - 565
EP - 586
JO - Annual Review of Genomics and Human Genetics
JF - Annual Review of Genomics and Human Genetics
ER -