The relationship of concentrations of serum hormones to pubertal gynecomastia

Peter A. Lee

Research output: Contribution to journalArticlepeer-review

100 Scopus citations


Pubertal gynecomastia occurred in 20 to 29 boys who were followed for 24 or more months during puberty. Mean concentrations of LH, FSH, prolactin, testosterone, and estrone and estradiol were compared. Although levels did not differ between boys who developed gynecomastia and those who did not, when compared with the stage of puberty, changes were noted between mean concentrations from samples before and when gynecomastia was first noted. A significant increase of estradiol occurred with the onset of gynecomastia, while testosterone levels did not change; thus the testosterone-estradiol ratio decreased. Prolactin concentrations fell significantly with the onset of gynecomastia. These data indicate a difference of hormonal dynamics between boys with and without gynecomastia.

Original languageEnglish (US)
Pages (from-to)212-215
Number of pages4
JournalThe Journal of Pediatrics
Issue number2
StatePublished - Feb 1975

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'The relationship of concentrations of serum hormones to pubertal gynecomastia'. Together they form a unique fingerprint.

Cite this