TY - JOUR
T1 - The relationship of concentrations of serum hormones to pubertal gynecomastia
AU - Lee, Peter A.
N1 - Funding Information:
From the Clinical Investigation Center, Naval Regional Medical Center, and the Reproductive Endocrinology Program, Department of Pathology, University of Michigan Medical Center. Supported in part by the Bureau of Medicine and Surgery, Navy Department, Jor CIP 4-48-365, and by a Program jProject grant in Reproductive Endocrinology ,from the National Institute of Child Health and Human Development of the United States Public Health Service (NIH-HD-05318). The opinions or assertions contained herein are the private ones of the author and are not to be interpreted as official or as reflecting the view of the Department of the Navy. Reprint address: Publications Office, Clinical Investigation Center, Naval Medical Research Unit, Oakland, Calif. 94627.
PY - 1975/2
Y1 - 1975/2
N2 - Pubertal gynecomastia occurred in 20 to 29 boys who were followed for 24 or more months during puberty. Mean concentrations of LH, FSH, prolactin, testosterone, and estrone and estradiol were compared. Although levels did not differ between boys who developed gynecomastia and those who did not, when compared with the stage of puberty, changes were noted between mean concentrations from samples before and when gynecomastia was first noted. A significant increase of estradiol occurred with the onset of gynecomastia, while testosterone levels did not change; thus the testosterone-estradiol ratio decreased. Prolactin concentrations fell significantly with the onset of gynecomastia. These data indicate a difference of hormonal dynamics between boys with and without gynecomastia.
AB - Pubertal gynecomastia occurred in 20 to 29 boys who were followed for 24 or more months during puberty. Mean concentrations of LH, FSH, prolactin, testosterone, and estrone and estradiol were compared. Although levels did not differ between boys who developed gynecomastia and those who did not, when compared with the stage of puberty, changes were noted between mean concentrations from samples before and when gynecomastia was first noted. A significant increase of estradiol occurred with the onset of gynecomastia, while testosterone levels did not change; thus the testosterone-estradiol ratio decreased. Prolactin concentrations fell significantly with the onset of gynecomastia. These data indicate a difference of hormonal dynamics between boys with and without gynecomastia.
UR - http://www.scopus.com/inward/record.url?scp=0016427657&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0016427657&partnerID=8YFLogxK
U2 - 10.1016/S0022-3476(75)80470-7
DO - 10.1016/S0022-3476(75)80470-7
M3 - Article
C2 - 1111683
AN - SCOPUS:0016427657
SN - 0022-3476
VL - 86
SP - 212
EP - 215
JO - The Journal of Pediatrics
JF - The Journal of Pediatrics
IS - 2
ER -