The remarkable evolutionary history of endornaviruses

Marilyn J. Roossinck, Sead Sabanadzovic, Ryo Okada, Rodrigo A. Valverde

Research output: Contribution to journalArticlepeer-review

83 Scopus citations


The family Endornaviridae contains several members from diverse hosts, including plants, fungi and oomycetes. They are found as large dsRNA elements with a nick in the coding strand. All members encode a conserved RNA-dependent RNA polymerase, but no other domain that is conserved among all members. Based on the conserved domain database comparison the various domains have different origins, indicating a highly modular evolutionary history. In some cases, domains with similar putative functions are found that are derived from different protein families, indicating convergent evolution for a required function.

Original languageEnglish (US)
Pages (from-to)2674-2678
Number of pages5
JournalJournal of General Virology
Issue number11
StatePublished - Nov 2011

All Science Journal Classification (ASJC) codes

  • Virology


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