The Risks and Benefits of Corticosteroid Injection vs. Platelet-Rich Plasma Injections in Patients

Haruki Ishii, Jina Libby, Lauren K. Poindexter, Amanda T. Wise, Ken Peyser, Surein Theivakumar, Tracy Espiritu McKay, Maria Janakos, Salvador E. Portugal

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of Review: This review aims to compare current evidence for the use of corticosteroid injection (CSI) versus platelet-rich plasma (PRP) in the treatment of common pathologies of the shoulder, hip and knee. Recent Findings: While recent studies suggest both PRP and CSI are efficacious treatments for various musculoskeletal conditions, the clinical significance of findings regarding PRP is often limited due to the heterogeneity of treatment protocols. Summary: Further research into optimal treatment protocols for both CSI and PRP is warranted. Some recent studies have suggested PRP to be superior to CSI in the treatment of greater trochanteric pain syndrome, patellar tendinopathy, low-grade medial collateral ligament injuries, and knee osteoarthritis. CSI may be more effective in the treatment of pes anserine bursitis and hip osteoarthritis.

Original languageEnglish (US)
Article number16
JournalCurrent Physical Medicine and Rehabilitation Reports
Volume13
Issue number1
DOIs
StatePublished - Dec 2025

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine
  • Rehabilitation

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