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The role of HFE genotype in macrophage phenotype
Anne M. Nixon
, Elizabeth Neely
, Ian A. Simpson
,
James R. Connor
Department of Neurosurgery
Department of Pediatrics
Penn State Cancer Institute
Penn State Neuroscience Institute
Cancer Institute, Experimental Therapeutics
Department of Neuroscience and Experimental Therapeutics
Research output
:
Contribution to journal
›
Article
›
peer-review
10
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Scopus citations
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Keyphrases
Genotype
100%
Macrophage Phenotype
100%
Macrophages
60%
Iron Homeostasis
60%
Cellular Iron
60%
Iron Release
60%
Gene Variants
40%
Transferrin
40%
Macrophage Function
40%
H63D
40%
Knock-in Mouse Model
20%
Inflammation
20%
Regulatory Mechanism
20%
IRP1
20%
Disease Progression
20%
Microglia
20%
Phagocytosis
20%
Pathogenic Process
20%
Mutant Protein
20%
L-ferritin
20%
Neurodegenerative Diseases
20%
Cellular Energy
20%
Iron Regulation
20%
Neurological Diseases
20%
Iron Loading
20%
Energy Production
20%
Disease Process
20%
Cytokine Expression
20%
Normal Function
20%
Iron Exposure
20%
Common Genes
20%
Phagocytic Activity
20%
HFE Gene
20%
Multiple Diseases
20%
Degenerative Process
20%
Brain Macrophages
20%
Infiltrating Macrophages
20%
Reparative Process
20%
BMP6
20%
Bone Marrow Macrophages
20%
Migration Activity
20%
Biochemistry, Genetics and Molecular Biology
Genotyping
100%
Macrophage
100%
Iron Homeostasis
42%
Cytokine
28%
Phagocytosis
28%
Transferrin
28%
Macrophage Function
28%
Secretion (Process)
14%
HFE (Gene)
14%
Mutant Protein
14%
Cell Energy
14%
Energy Yield
14%
Bone Morphogenetic Protein 6
14%
Ferritin
14%
Comorbidity
14%
Immunology and Microbiology
Macrophage
100%
Iron Homeostasis
42%
Phagocytosis
28%
Cytokine
28%
Macrophage Function
28%
Secretion (Process)
14%
Energy Yield
14%
Cell Energy
14%
Comorbidity
14%
Ferritin
14%
Pharmacology, Toxicology and Pharmaceutical Science
Iron
100%
Cytokine
18%
Transferrin
18%
Malignant Neoplasm
9%
Disease Exacerbation
9%
Inflammation
9%
Ferritin
9%
Mutant Protein
9%
Neurologic Disease
9%
Iron Regulatory Factor
9%
Bone Morphogenetic Protein 6
9%
Comorbidity
9%
Diseases
9%