The role of immunotherapy in in vitro fertilization: a guideline

Practice Committee of the American Society for Reproductive Medicine,, American Society for Reproductive Medicine, Birmingham, Alabama, USA

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Adjuvant immunotherapy treatments in in vitro fertilization (IVF) aim to improve the outcome of assisted reproductive technology (ART) in both the general ART population as well as subgroups such as patients with recurrent miscarriage or implantation failure. The purpose of this guideline is to evaluate the role of immunomodulating therapy in ART. Unfortunately, many of the evaluated therapies lack robust evidence from well-designed adequately powered randomized controlled trials to support their use. Immunotherapies reviewed in the present document are either not associated with improved live-birth outcome in IVF or have been insufficiently studied to make definitive recommendations.

Original languageEnglish (US)
Pages (from-to)387-400
Number of pages14
JournalFertility and sterility
Issue number3
StatePublished - Aug 2018

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology


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