TY - JOUR
T1 - The role of peripheral venous distension reflex in regulating hemodynamics
T2 - mini review
AU - Hamaoka, Takuto
AU - Sinoway, Lawrence I.
AU - Cui, Jian
N1 - Publisher Copyright:
© 2024
PY - 2024/12
Y1 - 2024/12
N2 - Significant volume is pooled in veins in humans and the amount is dramatically altered by various physiological stresses and diseases. Several animal and human studies demonstrated that limb venous distension evoked significant increases in blood pressure and sympathetic nerve activity (venous distension reflex, VDR). VDR has attracted much attention because of its potential to explain the still unknown mechanism of autonomic dysfunction in several diseases, which would lead to a new treatment approach. This mini review discusses accumulated evidence of VDR at this point and what should be investigated in the future to apply the current understanding of VDR in clinical practice.
AB - Significant volume is pooled in veins in humans and the amount is dramatically altered by various physiological stresses and diseases. Several animal and human studies demonstrated that limb venous distension evoked significant increases in blood pressure and sympathetic nerve activity (venous distension reflex, VDR). VDR has attracted much attention because of its potential to explain the still unknown mechanism of autonomic dysfunction in several diseases, which would lead to a new treatment approach. This mini review discusses accumulated evidence of VDR at this point and what should be investigated in the future to apply the current understanding of VDR in clinical practice.
UR - http://www.scopus.com/inward/record.url?scp=85203496695&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85203496695&partnerID=8YFLogxK
U2 - 10.1016/j.autneu.2024.103217
DO - 10.1016/j.autneu.2024.103217
M3 - Short survey
C2 - 39270515
AN - SCOPUS:85203496695
SN - 1566-0702
VL - 256
JO - Autonomic Neuroscience: Basic and Clinical
JF - Autonomic Neuroscience: Basic and Clinical
M1 - 103217
ER -
