TY - JOUR
T1 - The selection of comparators for randomized controlled trials of health-related behavioral interventions
T2 - recommendations of an NIH expert panel
AU - National Institutes of Health Office of Behavioral
AU - Social Sciences Research Expert Panel on Comparator Selection in Behavioral
AU - Social Science Clinical Trials
AU - Freedland, Kenneth E.
AU - King, Abby C.
AU - Ambrosius, Walter T.
AU - Mayo-Wilson, Evan
AU - Mohr, David C.
AU - Czajkowski, Susan M.
AU - Thabane, Lehana
AU - Collins, Linda M.
AU - Rebok, George W.
AU - Treweek, Shaun P.
AU - Cook, Thomas D.
AU - Edinger, Jack D.
AU - Stoney, Catherine M.
AU - Campo, Rebecca A.
AU - Young-Hyman, Deborah
AU - Riley, William T.
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/6
Y1 - 2019/6
N2 - Objectives: To provide recommendations for the selection of comparators for randomized controlled trials of health-related behavioral interventions. Study Design and Setting: The National Institutes of Health Office of Behavioral and Social Science Research convened an expert panel to critically review the literature on control or comparison groups for behavioral trials and to develop strategies for improving comparator choices and for resolving controversies and disagreements about comparators. Results: The panel developed a Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials. The model indicates that the optimal comparator is the one that best serves the primary purpose of the trial but that the optimal comparator's limitations and barriers to its use must also be taken into account. Conclusion: We developed best practice recommendations for the selection of comparators for health-related behavioral trials. Use of the Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials can improve the comparator selection process and help resolve disagreements about comparator choices.
AB - Objectives: To provide recommendations for the selection of comparators for randomized controlled trials of health-related behavioral interventions. Study Design and Setting: The National Institutes of Health Office of Behavioral and Social Science Research convened an expert panel to critically review the literature on control or comparison groups for behavioral trials and to develop strategies for improving comparator choices and for resolving controversies and disagreements about comparators. Results: The panel developed a Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials. The model indicates that the optimal comparator is the one that best serves the primary purpose of the trial but that the optimal comparator's limitations and barriers to its use must also be taken into account. Conclusion: We developed best practice recommendations for the selection of comparators for health-related behavioral trials. Use of the Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials can improve the comparator selection process and help resolve disagreements about comparator choices.
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U2 - 10.1016/j.jclinepi.2019.02.011
DO - 10.1016/j.jclinepi.2019.02.011
M3 - Review article
C2 - 30826377
AN - SCOPUS:85063902236
SN - 0895-4356
VL - 110
SP - 74
EP - 81
JO - Journal of Clinical Epidemiology
JF - Journal of Clinical Epidemiology
ER -