The state of antibody catalysis

David B. Smithrud, Stephen J. Benkovic

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


One of the fascinations of catalytic antibodies is the possibility of harnessing the mechanisms available to enzymes for chemical transformation and applying them to the broad realm of chemistry encountered in organic synthesis. Recently, the catalytic repertoire of antibodies has been extended to include mechanistically more complex bimolecular reactions and the immunological response to the hapten can be more thoroughly examined as a result of the advent of new screening technology using bacterial phages or auxotrophic cell lines.

Original languageEnglish (US)
Pages (from-to)459-466
Number of pages8
JournalCurrent Opinion in Biotechnology
Issue number4
StatePublished - Aug 1997

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering


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