The white dot syndromes

David A. Quillen, Janet B. Davis, Justin L. Gottlieb, Barbara A. Blodi, David G. Callanan, Tom S. Chang, Robert A. Equi

Research output: Contribution to journalArticlepeer-review

140 Scopus citations


Purpose To review the distinctive and shared features of the white dot syndromes, highlighting the clinical findings, diagnostic test results, proposed etiologies, treatments, and prognosis. Design Review. Methods Review of the literature. Results Common white dot syndromes are reviewed, including acute posterior multifocal placoid pigment epitheliopathy, birdshot chorioretinopathy, diffuse unilateral subacute neuroretinitis, multiple evanescent white dot syndrome, multifocal choroiditis with panuveitis, serpiginous choroiditis, and acute zonal occult outer retinopathy. Conclusions The white dot syndromes are a group of disorders characterized by multiple whitish-yellow inflammatory lesions located at the level of the outer retina, retinal pigment epithelium, and choroid. For clinicians and researchers alike, they present significant diagnostic and therapeutic challenges.

Original languageEnglish (US)
Pages (from-to)538-550
Number of pages13
JournalAmerican Journal of Ophthalmology
Issue number3
StatePublished - Mar 2004

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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