The world of phage tail-like bacteriocins: State of the art and biotechnological perspectives

Clara Ibarguren; Inés Bleriot; Lucia Blasco; Laura Fernández-García; Concha Ortiz-Cartagena; Lucia Arman; Antonio Barrio-Pujante; Olaya Menéndez Rodríguez; Rodolfo García-Contreras; Thomas K. Wood; María Tomás

doi:10.1016/j.micres.2025.128121

The world of phage tail-like bacteriocins: State of the art and biotechnological perspectives

Clara Ibarguren, Inés Bleriot, Lucia Blasco, Laura Fernández-García, Concha Ortiz-Cartagena, Lucia Arman, Antonio Barrio-Pujante, Olaya Menéndez Rodríguez, Rodolfo García-Contreras, Thomas K. Wood, María Tomás

Research output: Contribution to journal › Review article › peer-review

Abstract

In the struggle for resources, bacteria have developed different systems of competition, including the type VI secretion system (T6SS) and phage tail-like bacteriocins (PTLBs), that act by killing other bacterial species or strains from the same species. The emergence of antimicrobial resistance (AMR) is an urgent global health problem. In this context, the need to develop new antimicrobial agents has put PTLBs in the spotlight. This review focuses on the most relevant aspects of PTLBs such as their structural features, biology, the technological tools to improve their application, and the most importantly their patents.

Original language	English (US)
Article number	128121
Journal	Microbiological Research
Volume	295
DOIs	https://doi.org/10.1016/j.micres.2025.128121
State	Published - Jun 2025

All Science Journal Classification (ASJC) codes

Microbiology

Access to Document

10.1016/j.micres.2025.128121

Cite this

Ibarguren, C., Bleriot, I., Blasco, L., Fernández-García, L., Ortiz-Cartagena, C., Arman, L., Barrio-Pujante, A., Rodríguez, O. M., García-Contreras, R., Wood, T. K., & Tomás, M. (2025). The world of phage tail-like bacteriocins: State of the art and biotechnological perspectives. Microbiological Research, 295, Article 128121. https://doi.org/10.1016/j.micres.2025.128121

@article{4c24c3c61549493593de7cda6c5a62a1,

title = "The world of phage tail-like bacteriocins: State of the art and biotechnological perspectives",

abstract = "In the struggle for resources, bacteria have developed different systems of competition, including the type VI secretion system (T6SS) and phage tail-like bacteriocins (PTLBs), that act by killing other bacterial species or strains from the same species. The emergence of antimicrobial resistance (AMR) is an urgent global health problem. In this context, the need to develop new antimicrobial agents has put PTLBs in the spotlight. This review focuses on the most relevant aspects of PTLBs such as their structural features, biology, the technological tools to improve their application, and the most importantly their patents.",

author = "Clara Ibarguren and In{\'e}s Bleriot and Lucia Blasco and Laura Fern{\'a}ndez-Garc{\'i}a and Concha Ortiz-Cartagena and Lucia Arman and Antonio Barrio-Pujante and Rodr{\'i}guez, {Olaya Men{\'e}ndez} and Rodolfo Garc{\'i}a-Contreras and Wood, {Thomas K.} and Mar{\'i}a Tom{\'a}s",

note = "Publisher Copyright: {\textcopyright} 2025 The Authors",

year = "2025",

month = jun,

doi = "10.1016/j.micres.2025.128121",

language = "English (US)",

volume = "295",

journal = "Microbiological Research",

issn = "0944-5013",

publisher = "Elsevier GmbH",

}

TY - JOUR

T1 - The world of phage tail-like bacteriocins

T2 - State of the art and biotechnological perspectives

AU - Ibarguren, Clara

AU - Bleriot, Inés

AU - Blasco, Lucia

AU - Fernández-García, Laura

AU - Ortiz-Cartagena, Concha

AU - Arman, Lucia

AU - Barrio-Pujante, Antonio

AU - Rodríguez, Olaya Menéndez

AU - García-Contreras, Rodolfo

AU - Wood, Thomas K.

AU - Tomás, María

PY - 2025/6

Y1 - 2025/6

N2 - In the struggle for resources, bacteria have developed different systems of competition, including the type VI secretion system (T6SS) and phage tail-like bacteriocins (PTLBs), that act by killing other bacterial species or strains from the same species. The emergence of antimicrobial resistance (AMR) is an urgent global health problem. In this context, the need to develop new antimicrobial agents has put PTLBs in the spotlight. This review focuses on the most relevant aspects of PTLBs such as their structural features, biology, the technological tools to improve their application, and the most importantly their patents.

AB - In the struggle for resources, bacteria have developed different systems of competition, including the type VI secretion system (T6SS) and phage tail-like bacteriocins (PTLBs), that act by killing other bacterial species or strains from the same species. The emergence of antimicrobial resistance (AMR) is an urgent global health problem. In this context, the need to develop new antimicrobial agents has put PTLBs in the spotlight. This review focuses on the most relevant aspects of PTLBs such as their structural features, biology, the technological tools to improve their application, and the most importantly their patents.

UR - http://www.scopus.com/inward/record.url?scp=85218501894&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85218501894&partnerID=8YFLogxK

U2 - 10.1016/j.micres.2025.128121

DO - 10.1016/j.micres.2025.128121

M3 - Review article

C2 - 40015081

AN - SCOPUS:85218501894

SN - 0944-5013

VL - 295

JO - Microbiological Research

JF - Microbiological Research

M1 - 128121

ER -

The world of phage tail-like bacteriocins: State of the art and biotechnological perspectives

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this