Thematic review series: Skin Lipids. Sebaceous gland lipids: Friend or foe?

K. R. Smith, D. M. Thiboutot

Research output: Contribution to journalReview articlepeer-review

276 Scopus citations


Sebaceous glands are intriguing glands that are found throughout the human body except on the palms of the hands and soles of the feet. The true function of these glands has yet to be determined, but there are several theories, including antioxidant effects, antibacterial effects, and transport of pheromones. Sebaceous glands produce lipids that are involved in the pathogenesis of one of the most prevalent diseases of adolescence, acne. Although the majority of lipids produced by the sebaceous gland are also produced in other areas of the body, there are two that are characteristic of the sebaceous gland, wax esters and squalene. This review seeks to present an update on the physiology of the sebaceous glands, with particular emphasis on the production of sebaceous lipids.

Original languageEnglish (US)
Pages (from-to)271-281
Number of pages11
JournalJournal of Lipid Research
Issue number2
StatePublished - Feb 2008

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Endocrinology
  • Cell Biology


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