TY - GEN
T1 - Theoretical and experimental comparison of tissue phantoms using white light spectroscopy
AU - Popov, Kaloyan A.
AU - Kurzweg, Timothy P.
PY - 2011
Y1 - 2011
N2 - White light spectroscopy has the potential to be used as an optical biopsy method, as backscattered light data can be related to the cellular nucleus size. In this paper, we compare experimental backscattering results against the general Mie theory simulations. Our experimental technique obtains results in terms of intensity vs. wavelength. We also use optical filters, to limit the source spectrum, and when converting the backscattered data into the Fourier domain, we obtain characteristic frequencies which describe the scatterer size. Phantom tissues, comprised of polystyrene spheres in a liquid or gel, are used for the experiments.
AB - White light spectroscopy has the potential to be used as an optical biopsy method, as backscattered light data can be related to the cellular nucleus size. In this paper, we compare experimental backscattering results against the general Mie theory simulations. Our experimental technique obtains results in terms of intensity vs. wavelength. We also use optical filters, to limit the source spectrum, and when converting the backscattered data into the Fourier domain, we obtain characteristic frequencies which describe the scatterer size. Phantom tissues, comprised of polystyrene spheres in a liquid or gel, are used for the experiments.
UR - http://www.scopus.com/inward/record.url?scp=79953094013&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953094013&partnerID=8YFLogxK
U2 - 10.1117/12.875231
DO - 10.1117/12.875231
M3 - Conference contribution
AN - SCOPUS:79953094013
SN - 9780819484444
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Biomedical Applications of Light Scattering V
T2 - Biomedical Applications of Light Scattering V
Y2 - 22 January 2011 through 24 January 2011
ER -