TY - JOUR
T1 - Theoretical and Experimental Study on Temperature Elevation behind Ribs Caused by Weakly Focused Ultrasound
AU - Liu, Xiaozhou
AU - Yin, Chang
AU - Gong, Xiufen
AU - Cao, Wenwu
N1 - Funding Information:
Financial support for this work was provided by National Basic Research Program of China No. 2011CB707902 , the NIH under grant No. P41-EB21820 , National Natural Science Foundation of China under grant No. 11074122 and State Key Laboratory of Acoustics, Chinese Academy of Sciences .
PY - 2010/10
Y1 - 2010/10
N2 - Temperature distribution in tissues behind ribs produced by weakly focused ultrasound had been calculated using Pennes bioheat equation and the validity of the theoretical model was experimentally confirmed in vitro using porcine live. We found that the position of the maximum temperature in tissue is strongly influenced by the distance between the transducer and ribs, while the gap between ribs is the determining factor for the maximum achievable temperature. Within the focal length, when the distance between the transducer and ribs increases, the maximum temperature increases and its position shifts away from the transducer. The rib width has little effect on the position of the maximum temperature but affects the achievable peak temperature. Our results provide useful information for treating liver cancers using ultrasound induced hyperthermia. (E-mail: [email protected]).
AB - Temperature distribution in tissues behind ribs produced by weakly focused ultrasound had been calculated using Pennes bioheat equation and the validity of the theoretical model was experimentally confirmed in vitro using porcine live. We found that the position of the maximum temperature in tissue is strongly influenced by the distance between the transducer and ribs, while the gap between ribs is the determining factor for the maximum achievable temperature. Within the focal length, when the distance between the transducer and ribs increases, the maximum temperature increases and its position shifts away from the transducer. The rib width has little effect on the position of the maximum temperature but affects the achievable peak temperature. Our results provide useful information for treating liver cancers using ultrasound induced hyperthermia. (E-mail: [email protected]).
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U2 - 10.1016/j.ultrasmedbio.2010.07.018
DO - 10.1016/j.ultrasmedbio.2010.07.018
M3 - Article
C2 - 20800959
AN - SCOPUS:77956652649
SN - 0301-5629
VL - 36
SP - 1704
EP - 1712
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 10
ER -