Theoretical and Experimental Study on Temperature Elevation behind Ribs Caused by Weakly Focused Ultrasound

Xiaozhou Liu; Chang Yin; Xiufen Gong; Wenwu Cao

doi:10.1016/j.ultrasmedbio.2010.07.018

Theoretical and Experimental Study on Temperature Elevation behind Ribs Caused by Weakly Focused Ultrasound

Xiaozhou Liu, Chang Yin, Xiufen Gong, Wenwu Cao

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17 Scopus citations

Abstract

Temperature distribution in tissues behind ribs produced by weakly focused ultrasound had been calculated using Pennes bioheat equation and the validity of the theoretical model was experimentally confirmed in vitro using porcine live. We found that the position of the maximum temperature in tissue is strongly influenced by the distance between the transducer and ribs, while the gap between ribs is the determining factor for the maximum achievable temperature. Within the focal length, when the distance between the transducer and ribs increases, the maximum temperature increases and its position shifts away from the transducer. The rib width has little effect on the position of the maximum temperature but affects the achievable peak temperature. Our results provide useful information for treating liver cancers using ultrasound induced hyperthermia. (E-mail: dzk@psu.edu).

Original language	English (US)
Pages (from-to)	1704-1712
Number of pages	9
Journal	Ultrasound in Medicine and Biology
Volume	36
Issue number	10
DOIs	https://doi.org/10.1016/j.ultrasmedbio.2010.07.018
State	Published - Oct 2010

All Science Journal Classification (ASJC) codes

Radiological and Ultrasound Technology
Biophysics
Acoustics and Ultrasonics

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10.1016/j.ultrasmedbio.2010.07.018

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title = "Theoretical and Experimental Study on Temperature Elevation behind Ribs Caused by Weakly Focused Ultrasound",

abstract = "Temperature distribution in tissues behind ribs produced by weakly focused ultrasound had been calculated using Pennes bioheat equation and the validity of the theoretical model was experimentally confirmed in vitro using porcine live. We found that the position of the maximum temperature in tissue is strongly influenced by the distance between the transducer and ribs, while the gap between ribs is the determining factor for the maximum achievable temperature. Within the focal length, when the distance between the transducer and ribs increases, the maximum temperature increases and its position shifts away from the transducer. The rib width has little effect on the position of the maximum temperature but affects the achievable peak temperature. Our results provide useful information for treating liver cancers using ultrasound induced hyperthermia. (E-mail: dzk@psu.edu).",

author = "Xiaozhou Liu and Chang Yin and Xiufen Gong and Wenwu Cao",

note = "Funding Information: Financial support for this work was provided by National Basic Research Program of China No. 2011CB707902 , the NIH under grant No. P41-EB21820 , National Natural Science Foundation of China under grant No. 11074122 and State Key Laboratory of Acoustics, Chinese Academy of Sciences .",

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doi = "10.1016/j.ultrasmedbio.2010.07.018",

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T1 - Theoretical and Experimental Study on Temperature Elevation behind Ribs Caused by Weakly Focused Ultrasound

AU - Liu, Xiaozhou

AU - Yin, Chang

AU - Gong, Xiufen

AU - Cao, Wenwu

N1 - Funding Information: Financial support for this work was provided by National Basic Research Program of China No. 2011CB707902 , the NIH under grant No. P41-EB21820 , National Natural Science Foundation of China under grant No. 11074122 and State Key Laboratory of Acoustics, Chinese Academy of Sciences .

PY - 2010/10

Y1 - 2010/10

N2 - Temperature distribution in tissues behind ribs produced by weakly focused ultrasound had been calculated using Pennes bioheat equation and the validity of the theoretical model was experimentally confirmed in vitro using porcine live. We found that the position of the maximum temperature in tissue is strongly influenced by the distance between the transducer and ribs, while the gap between ribs is the determining factor for the maximum achievable temperature. Within the focal length, when the distance between the transducer and ribs increases, the maximum temperature increases and its position shifts away from the transducer. The rib width has little effect on the position of the maximum temperature but affects the achievable peak temperature. Our results provide useful information for treating liver cancers using ultrasound induced hyperthermia. (E-mail: dzk@psu.edu).

AB - Temperature distribution in tissues behind ribs produced by weakly focused ultrasound had been calculated using Pennes bioheat equation and the validity of the theoretical model was experimentally confirmed in vitro using porcine live. We found that the position of the maximum temperature in tissue is strongly influenced by the distance between the transducer and ribs, while the gap between ribs is the determining factor for the maximum achievable temperature. Within the focal length, when the distance between the transducer and ribs increases, the maximum temperature increases and its position shifts away from the transducer. The rib width has little effect on the position of the maximum temperature but affects the achievable peak temperature. Our results provide useful information for treating liver cancers using ultrasound induced hyperthermia. (E-mail: dzk@psu.edu).

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Theoretical and Experimental Study on Temperature Elevation behind Ribs Caused by Weakly Focused Ultrasound

Abstract

All Science Journal Classification (ASJC) codes

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