Theoretical basis for the identification of allelic variants that encode drug efficacy and toxicity

Keyphrases

• Single nucleotide Polymorphism 100%
• Drug Response 100%
• Drug Toxicity 100%
• Allelic Variants 100%
• Drug Efficacy 100%
• Genetic Variants 50%
• Population Genetic Parameters 50%
• Statistical Model 50%
• Response Rate 50%
• EM Algorithm 50%
• Human Population 50%
• Genetic Mapping 50%
• Adverse Effects 50%
• Pharmacodynamics 50%
• Combined Influence 50%
• Multiple Genes 50%
• Relative Strength 50%
• Residual Covariance Matrix 50%
• Mathematical Functions 50%
• Curvature Parameter 50%
• Statistical Properties 50%
• Specific DNA Sequence 50%
• Haplotype Mapping 50%
• DNA Sequence Variants 50%
• Simplex Algorithm 50%
• Pharmacogenetics and Pharmacogenomics 50%
• Sequence Mapping 50%

Biochemistry, Genetics and Molecular Biology

• Single-Nucleotide Polymorphism 100%
• Drug Response 100%
• Drug Toxicity 100%
• Drug Efficacy 100%
• Solution and Solubility 50%
• DNA Sequence 50%
• Genetic Divergence 50%
• Population Genetic Parameters 50%
• Pharmacogenetics 50%
• Pharmacogenomics 50%
• Pharmacodynamics 50%
• Haplotype Map 50%