Thermal and lewis acid catalyzed intramolecular ene reactions of allenylsilanes

Steven M. Weinreb, Daniel T. Smith, Jian Jin

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Intramolecular ene reactions of allenylsilanes can be effected with a variety of imines, aldehydes and alkenes as enophiles, forming five and six membered rings. These reactions are cis stereoselective in all cases studied, and appear to proceed via a concerted, pericyclic process. The cycloadditions all generally occur under mild thermal conditions and some involving imino enophiles can also be effected at lower temperatures using Lewis acid catalysis.

Original languageEnglish (US)
Pages (from-to)509-521
Number of pages13
Issue numberSPEC. ISS. APR.
StatePublished - Apr 1998

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry


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