TY - JOUR
T1 - Thoracic irradiation of limited small cell lung cancer
T2 - Have we defined optimal dose, time, and fractionation?
AU - Wagner, Henry
PY - 1997/6
Y1 - 1997/6
N2 - There is a general agreement that patients with limited small cell lung cancer (L-SCLC) are better treated with a combination of thoracic radiation therapy (TRT) and systemic chemotherapy (CT) than with either modality alone. There is little agreement, however, and few data from prospective trials, to define optimal ways of combining these modalities. This article will review available data on radiation dose, timing, fractionation, and volume issues in an attempt to develop standards for current practice and suggest appropriate questions for future prospective clinical trials.
AB - There is a general agreement that patients with limited small cell lung cancer (L-SCLC) are better treated with a combination of thoracic radiation therapy (TRT) and systemic chemotherapy (CT) than with either modality alone. There is little agreement, however, and few data from prospective trials, to define optimal ways of combining these modalities. This article will review available data on radiation dose, timing, fractionation, and volume issues in an attempt to develop standards for current practice and suggest appropriate questions for future prospective clinical trials.
UR - http://www.scopus.com/inward/record.url?scp=0342601446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0342601446&partnerID=8YFLogxK
U2 - 10.1016/S0169-5002(97)00647-8
DO - 10.1016/S0169-5002(97)00647-8
M3 - Article
C2 - 9213310
AN - SCOPUS:0342601446
SN - 0169-5002
VL - 17
SP - S137-S148
JO - Lung Cancer
JF - Lung Cancer
IS - SUPPL. 1
ER -