TY - JOUR
T1 - Thromboembolism After Total Hip Reconstruction
T2 - Failure of Low Doses of Heparin in Prevention
AU - Evarts, Charles M.
AU - Alfidi, Ralph J.
PY - 1973/7/30
Y1 - 1973/7/30
N2 - Twenty-five patients undergoing total hip replacement received low doses of heparin sodium. Phlebography was used for the diagnosis of deep venous thrombosis. Five thousand international units (IU) of heparin were given subcutaneously two hours preoperatively, 5,000 IU postoperatively the night of surgery, and every 12 hours for the next seven to ten days. Venous thrombosis developed in seven of 25 patients. Pulmonary embolism occurred in six patients. Until further studies are forthcoming, the utmost caution is urged in the use of low doses of heparin as a prophylactic agent after total hip reconstruction.
AB - Twenty-five patients undergoing total hip replacement received low doses of heparin sodium. Phlebography was used for the diagnosis of deep venous thrombosis. Five thousand international units (IU) of heparin were given subcutaneously two hours preoperatively, 5,000 IU postoperatively the night of surgery, and every 12 hours for the next seven to ten days. Venous thrombosis developed in seven of 25 patients. Pulmonary embolism occurred in six patients. Until further studies are forthcoming, the utmost caution is urged in the use of low doses of heparin as a prophylactic agent after total hip reconstruction.
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U2 - 10.1001/jama.1973.03220320045013
DO - 10.1001/jama.1973.03220320045013
M3 - Article
C2 - 4740341
AN - SCOPUS:0015940217
SN - 0098-7484
VL - 225
SP - 515
EP - 516
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
IS - 5
ER -