TY - JOUR
T1 - Tissue engineering
T2 - A promising therapeutic approach to necrotizing enterocolitis
AU - Grant, Christa N.
AU - Grikscheit, Tracy C.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013/5
Y1 - 2013/5
N2 - Tissue engineering is a promising potential candidate for treating intestinal failure resulting from necrotizing enterocolitis. This requires the acquisition, preparation and implantation of autologous organoid units. This may be affected by the complexities of periods of storage of viable donor tissue and delayed implantation. This chapter addresses the development, methodology, and application of tissue-engineered intestine in the experimental and clinical setting. Tissue engineering has the potential of avoiding the inherent toxicities of intestinal transplantation and prolonged immunosuppression.
AB - Tissue engineering is a promising potential candidate for treating intestinal failure resulting from necrotizing enterocolitis. This requires the acquisition, preparation and implantation of autologous organoid units. This may be affected by the complexities of periods of storage of viable donor tissue and delayed implantation. This chapter addresses the development, methodology, and application of tissue-engineered intestine in the experimental and clinical setting. Tissue engineering has the potential of avoiding the inherent toxicities of intestinal transplantation and prolonged immunosuppression.
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U2 - 10.1053/j.sempedsurg.2013.01.008
DO - 10.1053/j.sempedsurg.2013.01.008
M3 - Article
C2 - 23611615
AN - SCOPUS:84876730280
SN - 1055-8586
VL - 22
SP - 112
EP - 116
JO - Seminars in pediatric surgery
JF - Seminars in pediatric surgery
IS - 2
ER -