@inproceedings{2d9f0c259a4049bb93c9c3c6791345c1,
title = "Topology, dynamics, and control in cortical blood flow elucidated with optical techniques",
abstract = "Blood is a limited resource that supplies neurons and glia with nutriments. How is blood distributed both in a fail-safe way and in response to changing metabolic loads? We examine this issue in rodent cortex. First, in terms of topology, all-optical histology is used to reconstruct the vasculature network. Second, in terms of dynamics, the flux of blood cells in individual vessels is measured in response to neuronal activation and/or the perturbation of flow of a targeted vessel via plasma-mediated ablation. Lastly, in terms of control, optical indicators of neurovascular signaling molecules that alter vessel diameter are measured.",
author = "Tsai, {Philbert S.} and Pablo Blinder and Drew, {Patrick James} and Jonathan Driscoll and Diana Jeong and Kaufhold, {John P.} and Andy Shih and Ilya Valmianski and David Kleinfeld",
year = "2009",
doi = "10.1117/12.829588",
language = "English (US)",
isbn = "9780819476876",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
booktitle = "Biosensing II",
note = "Biosensing II ; Conference date: 04-08-2009 Through 06-08-2009",
}