TY - JOUR
T1 - Total mesorectal excision
T2 - What are we doing?
AU - Stewart, David B.
AU - Dietz, David W.
PY - 2007/8
Y1 - 2007/8
N2 - The introduction of total mesorectal excision (TME) for rectal cancer has reduced local recurrence rates and improved oncologic outcomes, although complication rates such as anastomotic leak have also been a consequence. With the advent of neoadjuvant therapy for rectal cancer, many are questioning how this development may change the role of TME. This review presents a history of how TME evolved and a description of this technique. Complication rates, the impact of neoadjuvant therapy on local recurrence, variations of TME such as nerve-sparing proctectomy and cancer-specific mesorectal excision, and a review of functional outcomes for various methods of reconstruction are presented.
AB - The introduction of total mesorectal excision (TME) for rectal cancer has reduced local recurrence rates and improved oncologic outcomes, although complication rates such as anastomotic leak have also been a consequence. With the advent of neoadjuvant therapy for rectal cancer, many are questioning how this development may change the role of TME. This review presents a history of how TME evolved and a description of this technique. Complication rates, the impact of neoadjuvant therapy on local recurrence, variations of TME such as nerve-sparing proctectomy and cancer-specific mesorectal excision, and a review of functional outcomes for various methods of reconstruction are presented.
UR - http://www.scopus.com/inward/record.url?scp=34547921669&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34547921669&partnerID=8YFLogxK
U2 - 10.1055/s-2007-984863
DO - 10.1055/s-2007-984863
M3 - Review article
C2 - 20011200
AN - SCOPUS:34547921669
SN - 1531-0043
VL - 20
SP - 190
EP - 202
JO - Clinics in Colon and Rectal Surgery
JF - Clinics in Colon and Rectal Surgery
IS - 3
ER -
