Total synthesis of celogentin C by stereoselective C-H activation

Yiqing Feng; Gong Chen

doi:10.1002/anie.200905134

Total synthesis of celogentin C by stereoselective C-H activation

Yiqing Feng, Gong Chen

Chemistry

Research output: Contribution to journal › Article › peer-review

288 Scopus citations

Abstract

(Figure Presented) A total gent: Inspired by the biosynthesis of celogentin C, a highly stereoselective and efficient palladium-catalyzed C-H functionalization strategy is employed to construct the key Leu-Trp linkage of this bicyclic compound. A streamlined synthesis is completed in 23 steps from simple amino acid building blocks.

Original language	English (US)
Pages (from-to)	958-961
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	5
DOIs	https://doi.org/10.1002/anie.200905134
State	Published - Jan 25 2010

All Science Journal Classification (ASJC) codes

Catalysis
General Chemistry

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10.1002/anie.200905134

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title = "Total synthesis of celogentin C by stereoselective C-H activation",

abstract = "(Figure Presented) A total gent: Inspired by the biosynthesis of celogentin C, a highly stereoselective and efficient palladium-catalyzed C-H functionalization strategy is employed to construct the key Leu-Trp linkage of this bicyclic compound. A streamlined synthesis is completed in 23 steps from simple amino acid building blocks.",

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AB - (Figure Presented) A total gent: Inspired by the biosynthesis of celogentin C, a highly stereoselective and efficient palladium-catalyzed C-H functionalization strategy is employed to construct the key Leu-Trp linkage of this bicyclic compound. A streamlined synthesis is completed in 23 steps from simple amino acid building blocks.

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Total synthesis of celogentin C by stereoselective C-H activation

Abstract

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